Central to the impacts of CD4 T cells, both positive in settings of infectious disease and
cancer and negative in the settings of autoimmunity and allergy, is their ability to differentiate …

Background The immune microenvironment is of great significance in cervical cancer.
However, there is still a lack of systematic research on the immune infiltration environment of …

Background Single-cell sequencing provides detailed insights into biological processes
including cell differentiation and identity. While providing deep cell-specific information, the …

Background: Osteosarcoma typically occurs in adolescents, and the survival rate of patients
with metastatic and recurrent osteosarcoma remains low. Abnormal regulation of alternative …

Acute respiratory distress syndrome (ARDS), a progressive status of acute lung injury (ALI),
is primarily caused by an immune-mediated inflammatory disorder, which can be an acute …

Hepatocellular carcinoma (HCC) accounts for third most cancer death globally, and its
prognosis continues to be poor even with many novel therapeutic approaches emerging …

Background Hint1 is a novel tumor suppressor gene, and inactivation of its expression is
closely associated with the carcinogenesis of a variety of malignancies. The effects of Hint1 …

Objective. Liver carcinoma is a common malignant tumor. In this study, an orthotopic liver
carcinoma model was established by B-ultrasound, and the therapeutic effect of sinomenine …

Objective To explore the mechanism of E2F transcription Factor 1 (E2F-1)-mediated ataxia-
telangiectasia-mutated protein (ATM) in cisplatin (DDP)-resistant nasopharyngeal …

Ovarian cancer (OC) is identified as one of the most aggressive malignant diseases that
imperil women health. Anoikis has been proved to be significantly correlated with the …