[HTML][HTML] Microglial regional heterogeneity and its role in the brain

YL Tan, Y Yuan, L Tian - Molecular psychiatry, 2020 - nature.com
Microglia have been recently shown to manifest a very interesting phenotypical
heterogeneity across different regions in the mammalian central nervous system (CNS) …

[HTML][HTML] Genetic variation, brain, and intelligence differences

IJ Deary, SR Cox, WD Hill - Molecular psychiatry, 2022 - nature.com
Individual differences in human intelligence, as assessed using cognitive test scores, have a
well-replicated, hierarchical phenotypic covariance structure. They are substantially stable …

Standardizing workflows in imaging transcriptomics with the abagen toolbox

RD Markello, A Arnatkeviciute, JB Poline, BD Fulcher… - elife, 2021 - elifesciences.org
Gene expression fundamentally shapes the structural and functional architecture of the
human brain. Open-access transcriptomic datasets like the Allen Human Brain Atlas provide …

A practical guide to linking brain-wide gene expression and neuroimaging data

A Arnatkevic̆iūtė, BD Fulcher, A Fornito - Neuroimage, 2019 - Elsevier
The recent availability of comprehensive, brain-wide gene expression atlases such as the
Allen Human Brain Atlas (AHBA) has opened new opportunities for understanding how …

[HTML][HTML] Neuronal timescales are functionally dynamic and shaped by cortical microarchitecture

R Gao, RL Van den Brink, T Pfeffer, B Voytek - Elife, 2020 - elifesciences.org
Complex cognitive functions such as working memory and decision-making require
information maintenance over seconds to years, from transient sensory stimuli to long-term …

Virtual histology of cortical thickness and shared neurobiology in 6 psychiatric disorders

Y Patel, N Parker, J Shin, D Howard, L French… - JAMA …, 2021 - jamanetwork.com
Importance Large-scale neuroimaging studies have revealed group differences in cortical
thickness across many psychiatric disorders. The underlying neurobiology behind these …

[HTML][HTML] New insights into the dynamic development of the cerebral cortex in childhood and adolescence: Integrating macro-and microstructural MRI findings

LB Norbom, L Ferschmann, N Parker, I Agartz… - Progress in …, 2021 - Elsevier
Through dynamic transactional processes between genetic and environmental factors,
childhood and adolescence involve reorganization and optimization of the cerebral cortex …

[HTML][HTML] Cell type-specific manifestations of cortical thickness heterogeneity in schizophrenia

MA Di Biase, MP Geaghan, WR Reay, J Seidlitz… - Molecular …, 2022 - nature.com
Brain morphology differs markedly between individuals with schizophrenia, but the cellular
and genetic basis of this heterogeneity is poorly understood. Here, we sought to determine …

Molecular properties underlying regional vulnerability to Alzheimer's disease pathology

MJ Grothe, J Sepulcre, G Gonzalez-Escamilla… - Brain, 2018 - academic.oup.com
Amyloid deposition and neurofibrillary degeneration in Alzheimer's disease specifically
affect discrete neuronal systems, but the underlying mechanisms that render some brain …

Consortium neuroscience of attention deficit/hyperactivity disorder and autism spectrum disorder: The ENIGMA adventure

M Hoogman, D Van Rooij, M Klein… - Human brain …, 2022 - Wiley Online Library
Neuroimaging has been extensively used to study brain structure and function in individuals
with attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) over …