Viral infections are closely linked to wheezing illnesses in children of all ages. Respiratory
syncytial virus (RSV) is the main causative agent of bronchiolitis, whereas rhinovirus (RV) is …

Respiratory syncytial virus (RSV) is amongst the most important pathogenic infections of
childhood and is associated with significant morbidity and mortality. Although there have …

Background Respiratory syncytial virus (RSV) is a major cause of hospitalisation in infants.
The burden of RSV infection in healthy term infants has not yet been established. Accurate …

The nasopharynx (NP) is a reservoir for microbes associated with acute respiratory
infections (ARIs). Lung inflammation resulting from ARIs during infancy is linked to asthma …

Respiratory infectious diseases are mainly caused by viruses or bacteria that often interact
with one another. Although their presence is a prerequisite for subsequent infections …

Background The global burden of disease attributable to seasonal influenza virus in children
is unknown. We aimed to estimate the global incidence of and mortality from lower …

Background Human metapneumovirus is a common virus associated with acute lower
respiratory infections (ALRIs) in children. No global burden estimates are available for ALRIs …

In global terms, respiratory viral infection is a major cause of morbidity and mortality. Infancy,
in particular, is a time of increased disease susceptibility and severity. Early-life viral …

Repeated cycles of infection-associated lower airway inflammation drive the pathogenesis
of persistent wheezing disease in children. In this study, the occurrence of acute respiratory …

Background Previous systematic reviews have not shown clear benefit of glucocorticoids for
acute viral bronchiolitis, but their use remains considerable. Recent large trials add …