Impact of diet and the bacterial microbiome on the mucous barrier and immune disorders
The prevalence of chronic immune and metabolic disorders is increasing rapidly. In
particular, inflammatory bowel diseases, obesity, diabetes, asthma and chronic obstructive …
particular, inflammatory bowel diseases, obesity, diabetes, asthma and chronic obstructive …
IL-17 in the lung: the good, the bad, and the ugly
SJ Gurczynski, BB Moore - American Journal of Physiology …, 2018 - journals.physiology.org
The IL-17 family of cytokines has emerged over the last two decades as a pleiotropic group
of molecules that function in a wide variety of both beneficial and detrimental (pathological) …
of molecules that function in a wide variety of both beneficial and detrimental (pathological) …
Expression of IL-22 in the skin causes Th2-biased immunity, epidermal barrier dysfunction, and pruritus via stimulating epithelial Th2 cytokines and the GRP pathway
Increased expression of Th22 cytokine IL-22 is a characteristic finding in atopic dermatitis
(AD). However, the specific role of IL-22 in the pathogenesis of AD in vivo has yet to be …
(AD). However, the specific role of IL-22 in the pathogenesis of AD in vivo has yet to be …
Activation of resolution pathways to prevent and fight chronic inflammation: lessons from asthma and inflammatory bowel disease
C Barnig, T Bezema, PC Calder, A Charloux… - Frontiers in …, 2019 - frontiersin.org
Formerly considered as a passive process, the resolution of acute inflammation is now
recognized as an active host response, with a cascade of coordinated cellular and …
recognized as an active host response, with a cascade of coordinated cellular and …
[HTML][HTML] Role of Th17 cytokines in airway remodeling in asthma and therapy perspectives
V Margelidon-Cozzolino, A Tsicopoulos… - Frontiers in …, 2022 - frontiersin.org
Airway remodeling is a frequent pathological feature of severe asthma leading to permanent
airway obstruction in up to 50% of cases and to respiratory disability. Although structural …
airway obstruction in up to 50% of cases and to respiratory disability. Although structural …
[PDF][PDF] Chronic spontaneous urticaria: pathogenesis and treatment considerations
Measurement of biomarkers has been incorporated within clinical research of asthma to
characterize the population and to associate the disease with environmental and therapeutic …
characterize the population and to associate the disease with environmental and therapeutic …
[HTML][HTML] Targeting the IL-22/IL-22BP axis enhances tight junctions and reduces inflammation during influenza infection
KD Hebert, N McLaughlin, M Galeas-Pena, Z Zhang… - Mucosal …, 2020 - Elsevier
The seasonal burden of influenza coupled with the pandemic outbreaks of more pathogenic
strains underscore a critical need to understand the pathophysiology of influenza injury in …
strains underscore a critical need to understand the pathophysiology of influenza injury in …
Ginsenoside Rh1 attenuates ovalbumin-induced asthma by regulating Th1/Th2 cytokines balance
Q Li, C Zhai, G Wang, J Zhou, W Li… - Bioscience …, 2021 - academic.oup.com
ABSTRACT Ginsenoside Rh1 (Rh1) has anti-inflammatory effects in asthma mice, but the
underlying mechanism remains unclear. BALB/c mice were sensitized and challenged with …
underlying mechanism remains unclear. BALB/c mice were sensitized and challenged with …
Interleukin-17 pathophysiology and therapeutic intervention in cystic fibrosis lung infection and inflammation
D Hsu, P Taylor, D Fletcher… - Infection and …, 2016 - Am Soc Microbiol
Cystic fibrosis (CF) is characterized by an excessive neutrophilic inflammatory response
within the airway as a result of defective cystic fibrosis transmembrane receptor (CFTR) …
within the airway as a result of defective cystic fibrosis transmembrane receptor (CFTR) …
[HTML][HTML] Asthma biomarkers: do they bring precision medicine closer to the clinic?
Measurement of biomarkers has been incorporated within clinical research of asthma to
characterize the population and to associate the disease with environmental and therapeutic …
characterize the population and to associate the disease with environmental and therapeutic …