Impact of diet and the bacterial microbiome on the mucous barrier and immune disorders

CA Alemao, KF Budden, HM Gomez, SF Rehman… - Allergy, 2021 - Wiley Online Library
The prevalence of chronic immune and metabolic disorders is increasing rapidly. In
particular, inflammatory bowel diseases, obesity, diabetes, asthma and chronic obstructive …

IL-17 in the lung: the good, the bad, and the ugly

SJ Gurczynski, BB Moore - American Journal of Physiology …, 2018 - journals.physiology.org
The IL-17 family of cytokines has emerged over the last two decades as a pleiotropic group
of molecules that function in a wide variety of both beneficial and detrimental (pathological) …

Expression of IL-22 in the skin causes Th2-biased immunity, epidermal barrier dysfunction, and pruritus via stimulating epithelial Th2 cytokines and the GRP pathway

H Lou, J Lu, EB Choi, MH Oh, M Jeong… - The Journal of …, 2017 - journals.aai.org
Increased expression of Th22 cytokine IL-22 is a characteristic finding in atopic dermatitis
(AD). However, the specific role of IL-22 in the pathogenesis of AD in vivo has yet to be …

Activation of resolution pathways to prevent and fight chronic inflammation: lessons from asthma and inflammatory bowel disease

C Barnig, T Bezema, PC Calder, A Charloux… - Frontiers in …, 2019 - frontiersin.org
Formerly considered as a passive process, the resolution of acute inflammation is now
recognized as an active host response, with a cascade of coordinated cellular and …

[HTML][HTML] Role of Th17 cytokines in airway remodeling in asthma and therapy perspectives

V Margelidon-Cozzolino, A Tsicopoulos… - Frontiers in …, 2022 - frontiersin.org
Airway remodeling is a frequent pathological feature of severe asthma leading to permanent
airway obstruction in up to 50% of cases and to respiratory disability. Although structural …

[PDF][PDF] Chronic spontaneous urticaria: pathogenesis and treatment considerations

I Agache, L Rogozea… - Allergy, asthma & …, 2017 - synapse.koreamed.org
Measurement of biomarkers has been incorporated within clinical research of asthma to
characterize the population and to associate the disease with environmental and therapeutic …

[HTML][HTML] Targeting the IL-22/IL-22BP axis enhances tight junctions and reduces inflammation during influenza infection

KD Hebert, N McLaughlin, M Galeas-Pena, Z Zhang… - Mucosal …, 2020 - Elsevier
The seasonal burden of influenza coupled with the pandemic outbreaks of more pathogenic
strains underscore a critical need to understand the pathophysiology of influenza injury in …

Ginsenoside Rh1 attenuates ovalbumin-induced asthma by regulating Th1/Th2 cytokines balance

Q Li, C Zhai, G Wang, J Zhou, W Li… - Bioscience …, 2021 - academic.oup.com
ABSTRACT Ginsenoside Rh1 (Rh1) has anti-inflammatory effects in asthma mice, but the
underlying mechanism remains unclear. BALB/c mice were sensitized and challenged with …

Interleukin-17 pathophysiology and therapeutic intervention in cystic fibrosis lung infection and inflammation

D Hsu, P Taylor, D Fletcher… - Infection and …, 2016 - Am Soc Microbiol
Cystic fibrosis (CF) is characterized by an excessive neutrophilic inflammatory response
within the airway as a result of defective cystic fibrosis transmembrane receptor (CFTR) …

[HTML][HTML] Asthma biomarkers: do they bring precision medicine closer to the clinic?

I Agache, L Rogozea - Allergy, Asthma & Immunology Research, 2017 - ncbi.nlm.nih.gov
Measurement of biomarkers has been incorporated within clinical research of asthma to
characterize the population and to associate the disease with environmental and therapeutic …