ABSTRACT C-Myc overexpression is a common finding in pancreatic cancer and predicts
the aggressive behavior of cancer cells. It binds to the promoter of different genes, thereby …

The MYC transcription factor, encoded by the c‐MYC proto‐oncogene, is activated by
growth‐promoting signals, and is a key regulator of biosynthetic and metabolic pathways …

Triple-negative breast cancer (TNBC) represents the most aggressive breast cancer
subtype. Poor prognosis in TNBC is partly due to lack of efficacious targeted therapy and …

Simple Summary Treatment of pancreatic neuroendocrine neoplasms (PNEN) is
challenging since a subset of patients will have a metastatic disease at diagnosis and/or will …

Carcinoid syndrome represents a debilitating paraneoplastic disease, caused by the
secretion of several substances, occurring in about 10–40% of patients with well …

Signal transduction pathways transmit the information received from external and internal
cues and generate a response that allows the cell to adapt to changes in the surrounding …

Glutamine analogs are potent suppressors of general glutamine metabolism with anti-
cancer activity. 6-diazo-5-oxo-L-norleucine (DON) is an orally available glutamine analog …

Background This study aimed to understand the mechanism of action of deoxythymidylate
kinase (DTYMK) and its effect on the prognosis of patients with pancreatic cancer. So as to …

Alternative splicing is the molecular process that generates multiple mRNA variants from
single eukaryotic genes through variable assortment of their exons (1, 2). This process …

Pancreatic neuroendocrine neoplasms (PNENs) are biologically and clinically
heterogeneous neoplasms in which pathogenic alterations are often indiscernible …