Recent insights into the role of hormones during development and their functional regulation

Y Aref, SC Fat, E Ray - Frontiers in Endocrinology, 2024 - frontiersin.org
Introduction Hormones play a vital role in development from conception to birth and
throughout the human lifespan. These periods are logically divided into fetal development …

Clinical evidence of growth hormone for infertile women with diminished ovarian reserve undergoing IVF: a systematic review and meta-analysis

G Lin, X Zhong, S Li, L Xu - Frontiers in Endocrinology, 2023 - frontiersin.org
Objective To appraise the current randomized clinical trials (RCTs) for evidence of the
association of growth hormone (GH) with improved outcomes in infertile women with …

Growth hormone treatment improves the development of follicles and oocytes in prepubertal lambs

K Liu, L Zhang, Q Qi, J Li, F Yan, J Hou - Journal of Ovarian Research, 2023 - Springer
Background When prepubertal lambs are superovulated, the ovarian response to
gonadotropin stimulation has great individual difference and the collected oocytes have …

Normalization of puberty and adult height in girls with Turner syndrome: results of the Swedish Growth Hormone trials initiating transition into adulthood

B Kriström, C Ankarberg-Lindgren… - Frontiers in …, 2023 - frontiersin.org
Objective To study the impact of GH dose and age at GH start in girls with Turner syndrome
(TS), aiming for normal height and age at pubertal onset (PO) and at adult height (AH) …

Metabolic hormones are integral regulators of female reproductive health and function

F Athar, M Karmani, NM Templeman - Bioscience Reports, 2024 - portlandpress.com
The female reproductive system is strongly influenced by nutrition and energy balance. It is
well known that food restriction or energy depletion can induce suppression of reproductive …

Downregulation of homeobox A1 in human granulosa cells is involved in diminished ovarian reserve through promoting cell apoptosis and mitochondrial dysfunction

Q Chen, Q Chen, Y Song, Y Xiang, Q Li, Y Sang… - Molecular and Cellular …, 2024 - Elsevier
Granulosa cell apoptosis contributes to the occurrence of diminished ovarian reserve (DOR).
HOXA1, belonging to the HOX gene family, is involved in regulating cancer cell apoptosis …

Effects of decamethylcyclopentasiloxane on reproductive systems in female rats

J Lee, K Kim, SM Park, JS Kwon, EB Jeung - Toxics, 2023 - mdpi.com
The female reproductive system becomes fertile through the action of hormones involved in
the hypothalamic-pituitary-ovarian axis. On the other hand, estrogen-like endocrine …

The Impacts of Periconceptional Alcohol on Neonatal Ovaries and Subsequent Adult Fertility in the Rat

SE Steane, DJ Burgess, KM Moritz… - International Journal of …, 2024 - mdpi.com
Maternal exposures during pregnancy can impact the establishment of the ovarian reserve
in offspring, the lifetime supply of germ cells that determine a woman's reproductive lifespan …

Impact of long-acting growth hormone replacement therapy in adult growth hormone deficiency: comparison between adolescent, adult, and elderly patients

AY Kargi - Best Practice & Research Clinical Endocrinology & …, 2023 - Elsevier
The predominant features of the adult growth hormone deficiency (GHD) syndrome may vary
between patients of different age and age of onset of GHD. Evidence from clinical trials and …

Growth hormone proteoformics atlas created to promote predictive, preventive, and personalized approach in overall management of pituitary neuroendocrine tumors

L Yang, C Li, T Song, X Zhan - EPMA Journal, 2023 - Springer
Human growth hormone (GH) is the indispensable hormone for the maintenance of normal
physiological functions of the human body, including the growth, development, metabolism …