Genistein: an integrative overview of its mode of action, pharmacological properties, and health benefits

J Sharifi-Rad, C Quispe, M Imran, A Rauf… - Oxidative medicine …, 2021 - Wiley Online Library
Genistein is an isoflavone first isolated from the brooming plant Dyer's Genista tinctoria L.
and is widely distributed in the Fabaceae family. As an isoflavone, mammalian genistein …

Lifestyle, oxidative stress, and antioxidants: back and forth in the pathophysiology of chronic diseases

M Sharifi-Rad, NV Anil Kumar, P Zucca… - Frontiers in …, 2020 - frontiersin.org
Oxidative stress plays an essential role in the pathogenesis of chronic diseases such as
cardiovascular diseases, diabetes, neurodegenerative diseases, and cancer. Long term …

Chitosan nanoparticles as a promising tool in nanomedicine with particular emphasis on oncological treatment

J Sharifi-Rad, C Quispe, M Butnariu, LS Rotariu… - Cancer Cell …, 2021 - Springer
The study describes the current state of knowledge on nanotechnology and its utilization in
medicine. The focus in this manuscript was on the properties, usage safety, and potentially …

Pharmacological properties of chalcones: a review of preclinical including molecular mechanisms and clinical evidence

B Salehi, C Quispe, I Chamkhi, N El Omari… - Frontiers in …, 2021 - frontiersin.org
Chalcones are among the leading bioactive flavonoids with a therapeutic potential
implicated to an array of bioactivities investigated by a series of preclinical and clinical …

[HTML][HTML] COVID-19 pandemic and alcohol consumption: Impacts and interconnections

D Calina, T Hartung, I Mardare, M Mitroi, K Poulas… - Toxicology reports, 2021 - Elsevier
Alcohol consumption is associated with multiple diseases and might contribute to
vulnerability to SARS-CoV-2 infection. It can also catalyze exacerbations of mental and …

SARS-CoV-2 pathophysiology and its clinical implications: An integrative overview of the pharmacotherapeutic management of COVID-19

A Tsatsakis, D Calina, L Falzone, D Petrakis… - Food and Chemical …, 2020 - Elsevier
Common manifestations of COVID-19 are respiratory and can extend from mild symptoms to
severe acute respiratory distress. The severity of the illness can also extend from mild …

The Pharmacological Activities of Crocus sativus L.: A Review Based on the Mechanisms and Therapeutic Opportunities of its Phytoconstituents

M Butnariu, C Quispe, J Herrera-Bravo… - Oxidative medicine …, 2022 - Wiley Online Library
Crocus species are mainly distributed in North Africa, Southern and Central Europe, and
Western Asia, used in gardens and parks as ornamental plants, while Crocus sativus …

Neuropharmacological effects of quercetin: a literature-based review

MS Islam, C Quispe, R Hossain, MT Islam… - Frontiers in …, 2021 - frontiersin.org
Quercetin (QUR) is a natural bioactive flavonoid that has been lately very studied for its
beneficial properties in many pathologies. Its neuroprotective effects have been …

The therapeutic potential of anthocyanins: current approaches based on their molecular mechanism of action

B Salehi, J Sharifi-Rad, F Cappellini, Ž Reiner… - Frontiers in …, 2020 - frontiersin.org
Anthocyanins are natural phenolic pigments with biological activity. They are well-known to
have potent antioxidant and antiinflammatory activity, which explains the various biological …

Probiotics: versatile bioactive components in promoting human health

J Sharifi-Rad, CF Rodrigues, Z Stojanović-Radić… - Medicina, 2020 - mdpi.com
The positive impact of probiotic strains on human health has become more evident than ever
before. Often delivered through food, dietary products, supplements, and drugs, different …