Mitochondrial function in the human oocyte and embryo and their role in developmental competence

J Van Blerkom - Mitochondrion, 2011 - Elsevier
The role of mitochondria as a nexus of developmental regulation in mammalian oogenesis
and early embryogenesis is emerging from basic research in model species and from …

[HTML][HTML] Mitochondria in human oogenesis and preimplantation embryogenesis: engines of metabolism, ionic regulation and developmental competence

J Van Blerkom - Reproduction, 2004 - rep.bioscientifica.com
Mitochondria are the most abundant organelles in the mammalian oocyte and early embryo.
While their role in ATP production has long been known, only recently has their contribution …

Mitochondria in early mammalian development

J Van Blerkom - Seminars in cell & developmental biology, 2009 - Elsevier
The role of mitochondria as central determinants of development competence of oocytes
and preimplantation stage embryos is considered in the context of the diverse activities …

Environmental and epigenetic effects upon preimplantation embryo metabolism and development

RJ Chason, J Csokmay, JH Segars… - Trends in endocrinology …, 2011 - cell.com
In vitro fertilization has provided a unique window into the metabolic processes that drive
embryonic growth and development from a fertilized ovum to a competent blastocyst. Post …

Mitochondria as regulatory forces in oocytes, preimplantation embryos and stem cells

J Van Blerkom - Reproductive biomedicine online, 2008 - Elsevier
In addition to their role in generating energy (ATP), other possible regulatory functions for
mitochondria in the mature oocyte, preimplantation stage embryo and differentiating …

[HTML][HTML] Regulatory roles for mitochondria in the peri-implantation mouse blastocyst: possible origins and developmental significance of differential Δψm

J Van Blerkom, H Cox, P Davis - Reproduction, 2006 - rep.bioscientifica.com
Studies of mitochondria in mouse and human oocytes and preimplantation stage embryos
have focused primarily on their metabolic capacity to generate ATP. However, it is becoming …

[HTML][HTML] Potential long-term risks associated with maternal aging (the role of the mitochondria)

M Wilding - Fertility and sterility, 2015 - Elsevier
The mean age at which women create families in Western society is increasing. This is in
spite of the fact that reproduction in later life is subject to various difficulties, such as the …

The role of mitochondrial genome (mtDNA) in somatic and embryo cloning of mammals. A review

M Samiec - J Anim Feed Sci, 2005 - jafs.com.pl
Mitochondria are semiautonomous organelles that contain double-stranded (α-helix) circular
DNA molecules (mtDNAs) of about 16300 to 16500 base pairs (bp). The mtDNA encodes …

Роль морфологической оценки ооцита и эмбриона при использовании ВРТ (обзор литературы)

ОЕ Краснощока, ВЮ Смольникова… - Проблемы …, 2015 - elibrary.ru
В обзоре приведены данные о существующей классической практике визуальной
морфологической оценки ооцитов и эмбрионов в современной клинической …

Клинические характеристики пациенток с нарушением показателей раннего эмбриогенезав программах ЭКО

ТА Назаренко, КВ Краснопольская, НИ Сесина… - Проблемы …, 2019 - elibrary.ru
Цель исследования-установить клинико-анамнестические характеристики пациенток,
сопряженные с нарушениями эмбриологических показателей при проведении …