Navigating for reward

M Sosa, LM Giocomo - Nature Reviews Neuroscience, 2021 - nature.com
An organism's survival can depend on its ability to recall and navigate to spatial locations
associated with rewards, such as food or a home. Accumulating research has revealed that …

Thalamic subnetworks as units of function

DS Roy, Y Zhang, MM Halassa, G Feng - Nature neuroscience, 2022 - nature.com
The thalamus engages in various functions including sensory processing, attention, decision
making and memory. Classically, this diversity of function has been attributed to the nuclear …

[PDF][PDF] A taxonomy of transcriptomic cell types across the isocortex and hippocampal formation

Z Yao, CTJ Van Velthoven, TN Nguyen, J Goldy… - Cell, 2021 - cell.com
The isocortex and hippocampal formation (HPF) in the mammalian brain play critical roles in
perception, cognition, emotion, and learning. We profiled∼ 1.3 million cells covering the …

[PDF][PDF] Integrated morphoelectric and transcriptomic classification of cortical GABAergic cells

NW Gouwens, SA Sorensen, F Baftizadeh, A Budzillo… - Cell, 2020 - cell.com
Neurons are frequently classified into distinct types on the basis of structural, physiological,
or genetic attributes. To better constrain the definition of neuronal cell types, we …

[HTML][HTML] A connectome of the Drosophila central complex reveals network motifs suitable for flexible navigation and context-dependent action selection

BK Hulse, H Haberkern, R Franconville… - Elife, 2021 - elifesciences.org
Flexible behaviors over long timescales are thought to engage recurrent neural networks in
deep brain regions, which are experimentally challenging to study. In insects, recurrent …

[HTML][HTML] Plasticity of epididymal adipose tissue in response to diet-induced obesity at single-nucleus resolution

AK Sárvári, EL Van Hauwaert, LK Markussen… - Cell metabolism, 2021 - Elsevier
Adipose tissues display a remarkable ability to adapt to the dietary status. Here, we have
applied single-nucleus RNA-seq to map the plasticity of mouse epididymal white adipose …

Neuronal diversity and convergence in a visual system developmental atlas

MN Özel, F Simon, S Jafari, I Holguera, YC Chen… - Nature, 2021 - nature.com
Deciphering how neuronal diversity is established and maintained requires a detailed
knowledge of neuronal gene expression throughout development. In contrast to mammalian …

Preconfigured dynamics in the hippocampus are guided by embryonic birthdate and rate of neurogenesis

R Huszár, Y Zhang, H Blockus, G Buzsáki - Nature neuroscience, 2022 - nature.com
The incorporation of new information into the hippocampal network is likely to be
constrained by its innate architecture and internally generated activity patterns. However, the …

Multiomic profiling of the acute stress response in the mouse hippocampus

LM von Ziegler, A Floriou-Servou, R Waag… - Nature …, 2022 - nature.com
The acute stress response mobilizes energy to meet situational demands and re-establish
homeostasis. However, the underlying molecular cascades are unclear. Here, we use a brief …

Circuit and molecular architecture of a ventral hippocampal network

MM Gergues, KJ Han, HS Choi, B Brown… - Nature …, 2020 - nature.com
The ventral hippocampus (vHPC) is a critical hub in networks that process emotional
information. While recent studies have indicated that ventral CA1 (vCA1) projection neurons …