Over the past two decades, bile acids (BAs) have become established as important
signaling molecules that enable fine-tuned inter-tissue communication from the liver, their …

The diverse microbial community that inhabits the human gut has an extensive metabolic
repertoire that is distinct from, but complements the activity of mammalian enzymes in the …

Pu-erh tea displays cholesterol-lowering properties, but the underlying mechanism has not
been elucidated. Theabrownin is one of the most active and abundant pigments in Pu-erh …

Although obesity occurs in most of the patients with type 2 diabetes (T2D), a fraction of
patients with T2D are underweight or have normal weight. Several studies have linked the …

β-glucans are complex polysaccharides that are found in several plants and foods, including
mushrooms. β-glucans display an array of potentially therapeutic properties. β-glucans have …

Increasing evidence suggests Alzheimer's disease (AD) pathophysiology is influenced by
primary and secondary bile acids, the end product of cholesterol metabolism. We analyze …

Bile acids are important physiological agents for intestinal nutrient absorption and biliary
secretion of lipids, toxic metabolites, and xenobiotics. Bile acids also are signaling …

Cholestasis is an impairment of bile formation/flow at the level of the hepatocyte and/or
cholangiocyte. The first, and for the moment, most established medical treatment is the …

Bile acid (BA) has been reported to improve growth performance and play an important role
in lipid metabolism of fish. Five diets were formulated to investigate the effects of dietary bile …

The intracellular nuclear receptor farnesoid X receptor and the transmembrane G protein-
coupled receptor TGR5 respond to bile acids by activating transcriptional networks and/or …