Strategies employed in the design of antimicrobial peptides with enhanced proteolytic stability
Z Lai, X Yuan, H Chen, Y Zhu, N Dong, A Shan - Biotechnology Advances, 2022 - Elsevier
Due to the alarming developing rate of multidrug-resistant bacterial pathogens, the
development and modification of antimicrobial peptides (AMPs) are unprecedentedly active …
development and modification of antimicrobial peptides (AMPs) are unprecedentedly active …
Microtiter plate assays to assess antibiofilm activity against bacteria
Bacterial biofilms demonstrate high broad-spectrum adaptive antibiotic resistance and
cause two thirds of all infections, but there is a lack of approved antibiofilm agents. Unlike …
cause two thirds of all infections, but there is a lack of approved antibiofilm agents. Unlike …
[HTML][HTML] Antimicrobial peptide mimics for clinical use: does size matter?
The search for efficient antimicrobial therapies that can alleviate suffering caused by
infections from resistant bacteria is more urgent than ever before. Infections caused by multi …
infections from resistant bacteria is more urgent than ever before. Infections caused by multi …
Unnatural amino acids: Promising implications for the development of new antimicrobial peptides
X Wang, X Yang, Q Wang, D Meng - Critical Reviews in …, 2023 - Taylor & Francis
The increasing incidence and rapid spread of bacterial resistance to conventional antibiotics
are a serious global threat to public health, highlighting the need to develop new …
are a serious global threat to public health, highlighting the need to develop new …
[HTML][HTML] Peptide-coating combating antimicrobial contaminations: a review of covalent immobilization strategies for industrial applications
L Stillger, D Müller - Journal of Materials Science, 2022 - Springer
Many corrosion problems are caused by the presence of microorganisms, so-called
microbiologically influenced corrosion (MIC). A major representative of MIC-causing bacteria …
microbiologically influenced corrosion (MIC). A major representative of MIC-causing bacteria …
The chemistry and biology of guanidine secondary metabolites
Covering: 2017–2019 Guanidine natural products isolated from microorganisms, marine
invertebrates and terrestrial plants, amphibians and spiders, represented by non-ribosomal …
invertebrates and terrestrial plants, amphibians and spiders, represented by non-ribosomal …
Lysine Stapling Screening Provides Stable and Low Toxic Cationic Antimicrobial Peptides Combating Multidrug-Resistant Bacteria In Vitro and In Vivo
Y Hu, H Li, R Qu, T He, X Tang, W Chen… - Journal of Medicinal …, 2021 - ACS Publications
Cationic antimicrobial peptides (CAMPs) are promising for treatment of multidrug-resistant
(MDR) bacteria-caused infections. However, clinical application of CAMPs has been …
(MDR) bacteria-caused infections. However, clinical application of CAMPs has been …
Covalent immobilization of DJK-5 peptide on porous titanium for enhanced antibacterial effects and restrained inflammatory osteoclastogenesis
Y Wang, J Zhang, T Gao, N Zhang, J He… - Colloids and Surfaces B …, 2021 - Elsevier
Currently, implant-related bone infection characterized by aggravated infection-induced
inflammatory responses and osteolysis, remains a severe challenge in orthopedic surgery …
inflammatory responses and osteolysis, remains a severe challenge in orthopedic surgery …
Design of Proteolytic-Resistant Antifungal Peptides by Utilizing Minimum d-Amino Acid Ratios
Z Lai, X Yuan, W Chen, H Chen, B Li, Z Bi… - Journal of Medicinal …, 2024 - ACS Publications
Antifungal peptides are an appealing alternative to standard antifungal medicines due to
their unique mechanism of action and low-level resistance. However, their susceptibility to …
their unique mechanism of action and low-level resistance. However, their susceptibility to …
Lysine-homologue substitution: Impact on antimicrobial activity and proteolytic stability of cationic stapled heptapeptides
Numerous natural antimicrobial peptides (AMPs) exhibit a cationic amphipathic helical
conformation, wherein cationic amino acids, such as lysine and arginine, play pivotal roles …
conformation, wherein cationic amino acids, such as lysine and arginine, play pivotal roles …