Borrelia burgdorferi is the causative agent of Lyme disease and is transmitted to vertebrate
hosts by Ixodes spp. ticks. The spirochaete relies heavily on its arthropod host for basic …

Lyme disease (Lyme borreliosis) is a tick-borne, zoonosis of adults and children caused by
genospecies of the Borrelia burgdorferi sensu lato complex. The ailment, widespread …

Borrelia burgdorferi is the etiological agent of Lyme disease, a multisystemic, multistage,
inflammatory infection resulting in patients experiencing cardiac, neurological, and arthritic …

Borrelia (Borreliella) burgdorferi, along with closely related species, is the etiologic agent of
Lyme disease. The spirochete subsists in an enzootic cycle that encompasses acquisition …

Maintenance of Borrelia burgdorferi within its enzootic cycle requires a complex regulatory
pathway involving the alternative σ factors RpoN and RpoS and two ancillary trans-acting …

The RNA polymerase alternative σ factor RpoS in Borrelia burgdorferi (Bb), the Lyme
disease pathogen, is responsible for programmatic-positive and-negative gene regulation …

Lyme disease (LD) is an emerging zoonotic infection that is increasing in incidence in North
America, Europe, and Asia. With the development of safe and efficacious vaccines, LD can …

ABSTRACT The Lyme disease bacterium Borrelia burgdorferi is extremely host dependent,
with a small genome and correspondingly limited metabolism. As such, it is an excellent …

Lyme borreliosis (LB) is the most common tick-borne disease caused by the spirochete
Borrelia burgdorferi in North America and Borrelia afzelii or Borrelia garinii in Europe and …

Lyme borreliosis is the most prevalent tick-borne disease in the United States, infecting~
476,000 people annually. Borrelia spp. spirochetal bacteria are the causative agents of …