[HTML][HTML] Histone modification in NSCLC: molecular mechanisms and therapeutic targets

K Bajbouj, A Al-Ali, RK Ramakrishnan… - International journal of …, 2021 - mdpi.com
Lung cancer is the leading cause of cancer mortality in both genders, with non-small cell
lung cancer (NSCLC) accounting for about 85% of all lung cancers. At the time of diagnosis …

[HTML][HTML] Epigenetic alterations and inflammation as emerging use for the advancement of treatment in non-small cell lung cancer

S Yang, Y Huang, Q Zhao - Frontiers in Immunology, 2022 - frontiersin.org
Lung cancer remains one of the most common malignancies in the world. Nowadays, the
most common lung cancer is non-small cell lung cancer (NSCLC), namely …

Microbiome dysbiosis and epigenetic modulations in lung cancer: from pathogenesis to therapy

FH Khan, BA Bhat, BA Sheikh, L Tariq… - Seminars in Cancer …, 2022 - Elsevier
The lung microbiome plays an essential role in maintaining healthy lung function, including
host immune homeostasis. Lung microbial dysbiosis or disruption of the gut-lung axis can …

Invited Review: Dysregulation of chromatin remodellers in paediatric brain tumours–SMARCB1 and beyond

PD Johann - Neuropathology and Applied Neurobiology, 2020 - Wiley Online Library
Mutations in chromatin remodelling genes occur in approximately 25% of all human tumours
(Kadoch et al. Nat Genet 45: 592–601, 2013). The spectrum of alterations is broad and …

[HTML][HTML] The epigenetic silencing of microRNA-433 facilitates the malignant phenotypes of non-small cell lung cancer by targeting CREB1

W Wang, C Feng, W Zhang, Y Long - American journal of …, 2021 - ncbi.nlm.nih.gov
Objective: MicroRNAs (miRNAs) play a big role in the regulation of non-small cell lung
cancer (NSCLC) development. The objective of this study is to determine how DNA …

[HTML][HTML] Unraveling the Post-Translational Modifications and therapeutical approach in NSCLC pathogenesis

P Gulhane, S Singh - Translational Oncology, 2023 - Elsevier
Abstract Non-Small Cell Lung Cancer (NSCLC) is the most prevalent kind of lung cancer
with around 85% of total lung cancer cases. Despite vast therapies being available, the …

Inactivation of epigenetic regulators due to mutations in solid tumors

MV Nemtsova, DS Mikhaylenko, EB Kuznetsova… - Biochemistry …, 2020 - Springer
Main factors involved in carcinogenesis are associated with somatic mutations in oncogenes
and tumor suppressor genes representing changes in the DNA nucleotide sequence …

Bioinformatics analysis of differentially expressed genes and miRNAs in low-grade gliomas

MA Bendahou, A Ibrahimi… - Cancer …, 2020 - journals.sagepub.com
Low-grade glioma is the most common type of primary intracranial tumor. In the last 3 years,
new observations of molecular precursors in adults with gliomas have led to a modification …

[HTML][HTML] Epigenetic Regulation in the Development of Hepatitis B Virus-Related Hepatocellular Carcinoma

S Mahmoudvand, Z Ramezannia, A Kaki, S Shokri - 2024 - intechopen.com
Viruses are always dependent on their host in many ways. They especially rely on the
cellular machinery of the host cell for their replication. In this regard, epigenetic regulation is …

Epigenetic therapy in lung cancer

M Conroy, Á O'Connor, M Bailey-Whyte… - Epigenetic Cancer …, 2023 - Elsevier
Significant improvements in clinical outcomes for lung cancer patients have been achieved
over the past decade, and this is a result of the introduction of targeted therapies in …