Emerging themes in PDZ domain signaling: structure, function, and inhibition
X Liu, EJ Fuentes - International review of cell and molecular biology, 2019 - Elsevier
Abstract Post-synaptic density-95, disks-large and zonula occludens-1 (PDZ) domains are
small globular protein–protein interaction domains widely conserved from yeast to humans …
small globular protein–protein interaction domains widely conserved from yeast to humans …
Proteolytic regulation of alginate overproduction in Pseudomonas aeruginosa
FH Damron, JB Goldberg - Molecular microbiology, 2012 - Wiley Online Library
Pseudomonas aeruginosa, a Gram‐negative bacterium, is a significant opportunistic
pathogen associated with skin and soft tissue infections, nosocomial pneumonia and sepsis …
pathogen associated with skin and soft tissue infections, nosocomial pneumonia and sepsis …
The intellectual disability protein RAB39B selectively regulates GluA2 trafficking to determine synaptic AMPAR composition
ML Mignogna, M Giannandrea, A Gurgone… - Nature …, 2015 - nature.com
RAB39B is a member of the RAB family of small GTPases that controls intracellular vesicular
trafficking in a compartment-specific manner. Mutations in the RAB39B gene cause …
trafficking in a compartment-specific manner. Mutations in the RAB39B gene cause …
Calcium binding to PICK1 is essential for the intracellular retention of AMPA receptors underlying long-term depression
A Citri, S Bhattacharyya, C Ma, W Morishita… - Journal of …, 2010 - Soc Neuroscience
NMDA receptor (NMDAR)-dependent long-term depression (LTD) in the hippocampus is
mediated primarily by the calcium-dependent removal of AMPA receptors (AMPARs) from …
mediated primarily by the calcium-dependent removal of AMPA receptors (AMPARs) from …
Regulation of AMPA receptor trafficking by protein ubiquitination
J Widagdo, S Guntupalli, SE Jang… - Frontiers in Molecular …, 2017 - frontiersin.org
The molecular mechanisms underlying plastic changes in the strength and connectivity of
excitatory synapses have been studied extensively for the past few decades and remain the …
excitatory synapses have been studied extensively for the past few decades and remain the …
Postsynaptic proteins at excitatory synapses in the brain—relationship with depressive disorders
S Samojedny, E Czechowska… - International journal of …, 2022 - mdpi.com
Depressive disorders (DDs) are an increasingly common health problem that affects all age
groups. DDs pathogenesis is multifactorial. However, it was proven that stress is one of the …
groups. DDs pathogenesis is multifactorial. However, it was proven that stress is one of the …
Sortilin-related receptor SORCS3 is a postsynaptic modulator of synaptic depression and fear extinction
T Breiderhoff, GB Christiansen, LT Pallesen, C Vaegter… - PloS one, 2013 - journals.plos.org
SORCS3 is an orphan receptor of the VPS10P domain receptor family, a group of sorting
and signaling receptors central to many pathways in control of neuronal viability and …
and signaling receptors central to many pathways in control of neuronal viability and …
Oxidative stress underlies the ischemia/reperfusion-induced internalization and degradation of AMPA receptors
LM Achzet, CJ Davison, M Shea, I Sturgeon… - International Journal of …, 2021 - mdpi.com
Stroke is the fifth leading cause of death annually in the United States. Ischemic stroke
occurs when a blood vessel supplying the brain is occluded. The hippocampus is …
occurs when a blood vessel supplying the brain is occluded. The hippocampus is …
Fast AMPAR trafficking for a high‐frequency synaptic transmission
D Choquet - European Journal of Neuroscience, 2010 - Wiley Online Library
AMPA‐type glutamate receptors (AMPARs), as well as most other transmembrane proteins,
are not stable in the postsynaptic density as was previously thought, but undergo constant …
are not stable in the postsynaptic density as was previously thought, but undergo constant …
Scaffolding proteins of the post-synaptic density contribute to synaptic plasticity by regulating receptor localization and distribution: relevance for neuropsychiatric …
Synaptic plasticity represents the long lasting activity-related strengthening or weakening of
synaptic transmission, whose well-characterized types are the long term potentiation and …
synaptic transmission, whose well-characterized types are the long term potentiation and …