Optical sensing and imaging of pH values: Spectroscopies, materials, and applications

A Steinegger, OS Wolfbeis, SM Borisov - Chemical reviews, 2020 - ACS Publications
This is the first comprehensive review on methods and materials for use in optical sensing of
pH values and on applications of such sensors. The Review starts with an introduction that …

Raman spectroscopy for chemical biology research

K Dodo, K Fujita, M Sodeoka - Journal of the American Chemical …, 2022 - ACS Publications
In chemical biology research, various fluorescent probes have been developed and used to
visualize target proteins or molecules in living cells and tissues, yet there are limitations to …

Dual-state emission (DSE) in organic fluorophores: design and applications

JL Belmonte-Vázquez, YA Amador-Sánchez… - Chemistry of …, 2021 - ACS Publications
Organic luminescent materials have attracted significant attention in the past few years due
to their fascinating photophysical properties. Implementing these emissive organic …

Lighting up micro-/nanorobots with fluorescence

M Yang, X Guo, F Mou, J Guan - Chemical Reviews, 2022 - ACS Publications
Micro-/nanorobots (MNRs) can be autonomously propelled on demand in complex
biological environments and thus may bring revolutionary changes to biomedicines …

Molecular excited states through a machine learning lens

PO Dral, M Barbatti - Nature Reviews Chemistry, 2021 - nature.com
Theoretical simulations of electronic excitations and associated processes in molecules are
indispensable for fundamental research and technological innovations. However, such …

Accelerating bayesian optimization for biological sequence design with denoising autoencoders

S Stanton, W Maddox, N Gruver… - International …, 2022 - proceedings.mlr.press
Bayesian optimization (BayesOpt) is a gold standard for query-efficient continuous
optimization. However, its adoption for drug design has been hindered by the discrete, high …

mScarlet: a bright monomeric red fluorescent protein for cellular imaging

DS Bindels, L Haarbosch, L Van Weeren, M Postma… - Nature …, 2017 - nature.com
We report the engineering of mScarlet, a truly monomeric red fluorescent protein with record
brightness, quantum yield (70%) and fluorescence lifetime (3.9 ns). We developed mScarlet …

Stimuli-bioresponsive hydrogels as new generation materials for implantable, wearable, and disposable biosensors for medical diagnostics: Principles, opportunities …

A Barhoum, O Sadak, IA Ramirez, N Iverson - Advances in Colloid and …, 2023 - Elsevier
Hydrogels are excellent water-swollen polymeric materials for use in wearable, implantable,
and disposable biosensors. Hydrogels have unique properties such as low cost, ease of …

Focal adhesion dynamics in cellular function and disease

YG Mishra, B Manavathi - Cellular signalling, 2021 - Elsevier
Acting as a bridge between the cytoskeleton of the cell and the extra cellular matrix (ECM),
the cell-ECM adhesions with integrins at their core, play a major role in cell signalling to …

[HTML][HTML] Whole-brain imaging with single-cell resolution using chemical cocktails and computational analysis

EA Susaki, K Tainaka, D Perrin, F Kishino, T Tawara… - Cell, 2014 - cell.com
Systems-level identification and analysis of cellular circuits in the brain will require the
development of whole-brain imaging with single-cell resolution. To this end, we performed …