Selective progesterone receptor modulators (SPRMs) are a new class of compounds
developed to target the progesterone receptor (PR) with a mix of agonist and antagonist …

Endometrial cancer is the most common gynecological malignancy in developed countries
and represents the eighth leading cause of cancer related death in women. The growing …

Mifepristone (RU486) is a born‐for‐woman molecule discovered three decades ago. Unlike
those antihypertensive and antipsychotic pharmaceutical blockbusters, this abortifacient …

This study is the first to investigate the antiproliferative effect of eupatilin in human
endometrial cancer cells. Eupatilin, a naturally occurring flavonoid isolated from Artemisia …

Progestin resistance is the main obstacle to successful conservative therapy in young
endometrial cancer patients. To investigate the molecular events that lead to progestin …

Simple Summary Patients with endometrial hyperplasia (EH) and endometrial cancer (EC)
often fail conservative treatment due to progestin resistance. This article reviews the …

Abstract Background Matrix metalloproteinases (MMPs) are involved in the degradation of
protein components of the extracellular matrix and thus play an important role in tumor …

Antiprogestins constitute a group of compounds, developed since the early 1980s, that bind
progesterone receptors with different affinities. The first clinical uses for antiprogestins were …

OBJECTIVE: To investigate the effect of mesenchymal stem cells isolated from Wharton jelly
of umbilical cord (WJ-MSCs) on ameliorating damaged human endometrial stromal cells …

Antiprogestins constitute a group of compounds, developed since the early 1980s, that bind
progesterone receptors with different affinities. The first clinical uses for antiprogestins were …