[PDF][PDF] NGM282 improves liver fibrosis and histology in 12 weeks in patients with nonalcoholic steatohepatitis

SA Harrison, SJ Rossi, AH Paredes, JF Trotter… - …, 2020 - Wiley Online Library
NGM282, an engineered fibroblast growth factor 19 analogue, rapidly and significantly
reduced liver fat content in a multicenter, randomized, double‐blind, placebo‐controlled …

Nonalcoholic fatty liver disease: pathogenesis and disease spectrum

T Hardy, F Oakley, QM Anstee… - Annual review of …, 2016 - annualreviews.org
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of liver dysfunction in
the Western world and is increasing owing to its close association with obesity and insulin …

Noninvasive tools and risk of clinically significant portal hypertension and varices in compensated cirrhosis: the “Anticipate” study

JG Abraldes, C Bureau, H Stefanescu, S Augustin… - Hepatology, 2016 - journals.lww.com
In patients with compensated advanced chronic liver disease (cACLD), the presence of
clinically significant portal hypertension (CSPH) and varices needing treatment (VNT) bears …

[HTML][HTML] Non-invasive diagnosis of liver fibrosis and cirrhosis

Y Lurie, M Webb, R Cytter-Kuint… - World journal of …, 2015 - ncbi.nlm.nih.gov
The evaluation and follow up of liver fibrosis and cirrhosis have been traditionally performed
by liver biopsy. However, during the last 20 years, it has become evident that this “gold …

MRI and MRE for non-invasive quantitative assessment of hepatic steatosis and fibrosis in NAFLD and NASH: clinical trials to clinical practice

PS Dulai, CB Sirlin, R Loomba - Journal of hepatology, 2016 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) represents one of the most common causes of
chronic liver disease, and its prevalence is rising worldwide. The occurrence of non …

AISF position paper on nonalcoholic fatty liver disease (NAFLD): Updates and future directions

A Lonardo, F Nascimbeni, G Targher… - Digestive and Liver …, 2017 - Elsevier
This review summarizes our current understanding of nonalcoholic fatty liver disease
(NAFLD), a multi-factorial systemic disease resulting from a complex interaction between a …

A concise review of non-alcoholic fatty liver disease

NN Than, PN Newsome - Atherosclerosis, 2015 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic
syndrome and the incidence of which is rising rapidly due to the increasing epidemic of …

[HTML][HTML] Nonalcoholic fatty liver disease: Evolving paradigms

A Lonardo, F Nascimbeni, M Maurantonio… - World journal of …, 2017 - ncbi.nlm.nih.gov
In the last years new evidence has accumulated on nonalcoholic fatty liver disease (NAFLD)
challenging the paradigms that had been holding the scene over the previous 30 years …

A structurally optimized FXR agonist, MET409, reduced liver fat content over 12 weeks in patients with non-alcoholic steatohepatitis

SA Harrison, MR Bashir, KJ Lee, J Shim-Lopez… - Journal of …, 2021 - Elsevier
Background & Aims The benefits of farnesoid X receptor (FXR) agonists in patients with non-
alcoholic steatohepatitis (NASH) have been validated, although improvements in efficacy …

[HTML][HTML] Effectiveness of exercise in hepatic fat mobilization in non-alcoholic fatty liver disease: Systematic review

P Golabi, CT Locklear, P Austin, S Afdhal… - World journal of …, 2016 - ncbi.nlm.nih.gov
AIM: To investigate the efficacy of exercise interventions on hepatic fat mobilization in non-
alcoholic fatty liver disease (NAFLD) patients. METHODS: Ovid-Medline, PubMed, EMBASE …