Effects of moderate and vigorous exercise on nonalcoholic fatty liver disease: a randomized clinical trial

HJ Zhang, J He, LL Pan, ZM Ma, CK Han… - JAMA internal …, 2016 - jamanetwork.com
Importance Nonalcoholic fatty liver disease (NAFLD) is a prevalent risk factor for chronic
liver disease and cardiovascular disease. Objective To compare the effects of moderate and …

[HTML][HTML] Clinical utility of magnetic resonance imaging biomarkers for identifying nonalcoholic steatohepatitis patients at high risk of progression: a multicenter pooled …

A Andersson, M Kelly, K Imajo, A Nakajima… - Clinical …, 2022 - Elsevier
Background & Aims Nonalcoholic fatty liver disease (NAFLD) is increasing in prevalence
worldwide. NAFLD is associated with excess risk of all-cause mortality, and its progression …

Relationship between left ventricular structural and metabolic remodeling in type 2 diabetes

E Levelt, M Mahmod, SK Piechnik, R Ariga… - Diabetes, 2016 - Am Diabetes Assoc
Concentric left ventricular (LV) remodeling is associated with adverse cardiovascular events
and is frequently observed in patients with type 2 diabetes mellitus (T2DM). Despite this, the …

Ectopic and visceral fat deposition in lean and obese patients with type 2 diabetes

E Levelt, M Pavlides, R Banerjee, M Mahmod… - Journal of the American …, 2016 - jacc.org
Abstract Background: Type 2 diabetes (T2D) and obesity are associated with nonalcoholic
fatty liver disease, cardiomyopathy, and cardiovascular mortality. Both show stronger links …

Liver fibrosis: Review of current imaging and MRI quantification techniques

L Petitclerc, G Sebastiani, G Gilbert… - Journal of Magnetic …, 2017 - Wiley Online Library
Liver fibrosis is characterized by the accumulation of extracellular matrix proteins such as
collagen in the liver interstitial space. All causes of chronic liver disease may lead to fibrosis …

Liver iron quantification with MR imaging: a primer for radiologists

R Labranche, G Gilbert, M Cerny, KN Vu, D Soulières… - Radiographics, 2018 - pubs.rsna.org
Iron overload is a systemic disorder and is either primary (genetic) or secondary (exogenous
iron administration). Primary iron overload is most commonly associated with hereditary …

Exenatide decreases liver fat content and epicardial adipose tissue in patients with obesity and type 2 diabetes: a prospective randomized clinical trial using magnetic …

A Dutour, I Abdesselam, P Ancel… - Diabetes, Obesity …, 2016 - Wiley Online Library
Aim To conduct a prospective randomized trial to investigate the effect of glucagon‐like
peptide‐1 (GLP‐1) analogues on ectopic fat stores. Methods A total of 44 obese subjects …

Multiancestry exome sequencing reveals INHBE mutations associated with favorable fat distribution and protection from diabetes

P Akbari, OA Sosina, J Bovijn, K Landheer… - Nature …, 2022 - nature.com
Body fat distribution is a major, heritable risk factor for cardiometabolic disease, independent
of overall adiposity. Using exome-sequencing in 618,375 individuals (including 160,058 non …

Multiparametric magnetic resonance imaging for the assessment of non‐alcoholic fatty liver disease severity

M Pavlides, R Banerjee, EM Tunnicliffe… - Liver …, 2017 - Wiley Online Library
Abstract Background & Aims The diagnosis of non‐alcoholic steatohepatitis and fibrosis
staging are central to non‐alcoholic fatty liver disease assessment. We evaluated …

Diagnostic modalities of non-alcoholic fatty liver disease: from biochemical biomarkers to multi-omics non-invasive approaches

E Martinou, M Pericleous, I Stefanova, V Kaur… - Diagnostics, 2022 - mdpi.com
Non-Alcoholic Fatty Liver Disease (NAFLD) is currently the most common cause of chronic
liver disease worldwide, and its prevalence is increasing globally. NAFLD is a multifaceted …