Materials for oral delivery of proteins and peptides
TD Brown, KA Whitehead, S Mitragotri - Nature Reviews Materials, 2020 - nature.com
Throughout history, oral administration has been regarded as the most convenient mode of
drug delivery, as it requires minimal expertise and invasiveness. Although oral delivery …
drug delivery, as it requires minimal expertise and invasiveness. Although oral delivery …
Oral drug delivery platforms for biomedical applications
Oral administration is perhaps the most commonly used and acceptable route for drug
delivery to patients, mainly due to its non-invasiveness, simplicity, and versatility …
delivery to patients, mainly due to its non-invasiveness, simplicity, and versatility …
Chitosan and its derivatives for application in mucoadhesive drug delivery systems
Mucoadhesive drug delivery systems are desirable as they can increase the residence time
of drugs at the site of absorption/action, provide sustained drug release and minimize the …
of drugs at the site of absorption/action, provide sustained drug release and minimize the …
Surface modification of lipid-based nanoparticles
There is a growing interest in the development of lipid-based nanocarriers for multiple
purposes, including the recent increase of these nanocarriers as vaccine components …
purposes, including the recent increase of these nanocarriers as vaccine components …
Gold nanoparticles (GNPs) in biomedical and clinical applications: A review
Gold nanoparticles (GNPs) have been extensively used in various applications ranging from
environmental detection to biomedical applications. Due to their unique characteristics such …
environmental detection to biomedical applications. Due to their unique characteristics such …
[HTML][HTML] Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues
P Lundquist, P Artursson - Advanced drug delivery reviews, 2016 - Elsevier
In this contribution, we review the molecular and physiological barriers to oral delivery of
peptides and nanoparticles. We discuss the opportunities and predictivity of various in vitro …
peptides and nanoparticles. We discuss the opportunities and predictivity of various in vitro …
Stimulus-cleavable chemistry in the field of controlled drug delivery
Stimulus-cleavable nanoscale drug delivery systems are receiving significant attention
owing to their capability of achieving exquisite control over drug release via the exposure to …
owing to their capability of achieving exquisite control over drug release via the exposure to …
Role of metals in Alzheimer's disease
N Das, J Raymick, S Sarkar - Metabolic brain disease, 2021 - Springer
Metal homeostasis in the central nervous system (CNS) is a crucial component of healthy
brain function, because metals serve as enzymatic cofactors and are key components of …
brain function, because metals serve as enzymatic cofactors and are key components of …
Hypromellose–A traditional pharmaceutical excipient with modern applications in oral and oromucosal drug delivery
E Mašková, K Kubová, BT Raimi-Abraham… - Journal of controlled …, 2020 - Elsevier
Hydroxypropylmethylcellulose (HPMC), also known as Hypromellose, is a traditional
pharmaceutical excipient widely exploited in oral sustained drug release matrix systems …
pharmaceutical excipient widely exploited in oral sustained drug release matrix systems …
Transporter-guided delivery of nanoparticles to improve drug permeation across cellular barriers and drug exposure to selective cell types
Targeted nano-drug delivery systems conjugated with specific ligands to target selective cell-
surface receptors or transporters could enhance the efficacy of drug delivery and therapy …
surface receptors or transporters could enhance the efficacy of drug delivery and therapy …