Beyond the joints, the extra-articular manifestations in rheumatoid arthritis

A Conforti, I Di Cola, V Pavlych, P Ruscitti… - Autoimmunity …, 2021 - Elsevier
Rheumatoid arthritis (RA) is an inflammatory disease typically affecting the joints, but the
systemic inflammatory process may involve other tissues and organs. Many extra-articular …

The many facets of macrophages in rheumatoid arthritis

E Siouti, E Andreakos - Biochemical pharmacology, 2019 - Elsevier
Macrophages are central to the pathophysiology of rheumatoid arthritis (RA). They constitute
the main source of pro-inflammatory cytokines and chemokines such as TNF and IL-1β, they …

[HTML][HTML] The interplay between inflammation and metabolism in rheumatoid arthritis

MS Chimenti, P Triggianese, P Conigliaro… - Cell death & …, 2015 - nature.com
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by extensive
synovitis resulting in erosions of articular cartilage and marginal bone that lead to joint …

[HTML][HTML] Treatment of rheumatoid arthritis-associated interstitial lung disease: lights and shadows

G Cassone, A Manfredi, C Vacchi, F Luppi… - Journal of Clinical …, 2020 - mdpi.com
Rheumatoid arthritis (RA) is a chronic and systemic inflammatory disease affecting 0.5–1%
of the population worldwide. Interstitial lung disease (ILD) is a serious pulmonary …

Overlap connective tissue disease syndromes

L Iaccarino, M Gatto, S Bettio, F Caso… - Autoimmunity …, 2013 - Elsevier
Overlap Syndromes (OSs) have been defined as entities satisfying classification criteria of at
least two connective tissue diseases (CTDs) occurring at the same or at different times in the …

Extra-articular rheumatoid arthritis

C Turesson - Current opinion in rheumatology, 2013 - journals.lww.com
Extra-articular rheumatoid arthritis : Current Opinion in Rheumatology Extra-articular rheumatoid
arthritis : Current Opinion in Rheumatology Log in or Register Subscribe to journalSubscribe …

[HTML][HTML] Accelerated immunosenescence in rheumatoid arthritis: impact on clinical progression

ME Bauer - Immunity & Ageing, 2020 - Springer
Patients with rheumatoid arthritis (RA) develop features of accelerated ageing, including
immunosenescence. These changes include decreased thymic functionality, expansion of …

Benefits of exercise in patients with rheumatoid arthritis: a randomized controlled trial of a patient-specific exercise programme

M Azeez, C Clancy, T O'Dwyer, C Lahiff, F Wilson… - Clinical …, 2020 - Springer
Background Patients with rheumatoid arthritis (RA) tend to be more overweight, take less
physical exercise, exhibit decreased cardiorespiratory fitness and demonstrate reduced …

[HTML][HTML] Epidemiología, repercusión clínica y objetivos terapéuticos en la artrosis

V Mayoral Rojals - Revista de la Sociedad Española del Dolor, 2021 - SciELO Espana
La artrosis es uno de los principales problemas de salud en todos los países, más
prevalente en los países desarrollados probablemente debido a factores como el aumento …

Animal models of rheumatoid arthritis: How informative are they?

K McNamee, R Williams, M Seed - European journal of pharmacology, 2015 - Elsevier
Animal models of arthritis are widely used to de-convolute disease pathways and to identify
novel drug targets and therapeutic approaches. However, the high attrition rates of drugs in …