Recognizing and reversing the immunosuppressive tumor microenvironment of head and neck cancer
The estimated annual incidence of oral cavity and pharyngeal cancer is 39,000 in the United
States and 260,000 cases worldwide. Despite significant advances in surgery …
States and 260,000 cases worldwide. Despite significant advances in surgery …
Benign SNPs in the Coding Region of TP53: Finding the Needles in a Haystack of Pathogenic Variants
T Soussi - Cancer Research, 2022 - AACR
With the recent explosion in high-throughput genotyping technology, the amount and quality
of SNP data have increased exponentially, facilitating the discovery of multiple uncommon …
of SNP data have increased exponentially, facilitating the discovery of multiple uncommon …
In vitro and in vivo anti-tumor activity of Coenzyme Q0 against TWIST1-overexpressing HNSCC cells: ROS-mediated inhibition of EMT/metastasis and autophagy …
Abstract HNSCC (Head and Heck Squamous Cell Carcinoma) is a reasonably prevalent
cancer with a high mortality rate. In this study, we tried to examine the anti-metastasis and …
cancer with a high mortality rate. In this study, we tried to examine the anti-metastasis and …
[HTML][HTML] Development and validation of an autophagy-related LncRNA prognostic signature in head and neck squamous cell carcinoma
L Shen, N Li, Q Zhou, Z Li, L Shen - Frontiers in Oncology, 2021 - frontiersin.org
Head and neck squamous cell carcinoma (HNSCC) is one of the greatest public challenges
because of delayed diagnosis and poor prognosis. In this study, we established an …
because of delayed diagnosis and poor prognosis. In this study, we established an …
Is fibroblast growth factor receptor 4 a suitable target of cancer therapy?
C Heinzle, Z Erdem, J Paur… - Current …, 2014 - ingentaconnect.com
Fibroblast growth factors (FGF) and their tyrosine kinase receptors (FGFR) support cell
proliferation, survival and migration during embryonic development, organogenesis and …
proliferation, survival and migration during embryonic development, organogenesis and …
MART-10, a novel vitamin D analog, inhibits head and neck squamous carcinoma cells growth through cell cycle arrest at G0/G1 with upregulation of p21 and p27 and …
KC Chiang, CN Yeh, JT Hsu, LW Chen, SF Kuo… - The Journal of Steroid …, 2013 - Elsevier
For the head and neck squamous cell carcinoma (HNSCC), surgery in combination with
radiation therapy is the current standard treatment. However, the complex anatomy and …
radiation therapy is the current standard treatment. However, the complex anatomy and …
[HTML][HTML] DNA double-strand break response and repair gene polymorphisms may influence therapy results and prognosis in head and neck cancer patients
D Butkiewicz, M Krześniak, A Gdowicz-Kłosok… - Cancers, 2023 - mdpi.com
Simple Summary Head and neck cancer (HNC) is characterized by radio-and
chemoresistance contributing to treatment failure and poor prognosis. There is evidence that …
chemoresistance contributing to treatment failure and poor prognosis. There is evidence that …
[HTML][HTML] Fibroblast growth factor receptor family members as prognostic biomarkers in head and neck squamous cell carcinoma: a systematic review
NA Ipenburg, K Koole, KS Liem, PMW van Kempen… - Targeted …, 2016 - Springer
Background Since head and neck cancer is characterized by poor survival rates, there is a
demand for novel therapeutic targets and prognostic biomarkers. An upcoming therapeutic …
demand for novel therapeutic targets and prognostic biomarkers. An upcoming therapeutic …
The association between the XRCC1 Arg399Gln polymorphism and the risk of head and neck cancer: an updated meta-analysis including 14586 subjects
S Xia, S Wu, M Wang - Technology in cancer research & …, 2021 - journals.sagepub.com
Background: Accumulated evidence shows that DNA repair gene X-ray repair cross
complementing group 1 (XRCC1) may determine individual susceptibility to head and neck …
complementing group 1 (XRCC1) may determine individual susceptibility to head and neck …
FGFR4 is a potential predictive biomarker in oral and oropharyngeal squamous cell carcinoma
K Koole, PMW Van Kempen, LW Van Bockel, T Smets… - Pathobiology, 2015 - karger.com
Objective: The aim of this study was to investigate whether fibroblast growth factor receptor 4
(FGFR4) could serve as a potential therapeutic target, prognostic biomarker or biomarker …
(FGFR4) could serve as a potential therapeutic target, prognostic biomarker or biomarker …