Electrospinning: An enabling nanotechnology platform for drug delivery and regenerative medicine

S Chen, R Li, X Li, J Xie - Advanced drug delivery reviews, 2018 - Elsevier
Electrospinning provides an enabling nanotechnology platform for generating a rich variety
of novel structured materials in many biomedical applications including drug delivery …

[HTML][HTML] Functional hydrogels for the treatment of myocardial infarction

T Wu, W Liu - NPG Asia Materials, 2022 - nature.com
Myocardial infarction (MI) is a major disease posing a significant threat to human health, as it
leads to necrosis of numerous cardiomyocytes (CMs), left ventricle dilation, and cardiac …

Injectable granular hydrogels with multifunctional properties for biomedical applications

JE Mealy, JJ Chung, HH Jeong, D Issadore… - Advanced …, 2018 - Wiley Online Library
Injectable hydrogels are useful for numerous biomedical applications, such as to introduce
therapeutics into tissues or for 3D printing. To expand the complexity of available injectable …

A perfusable, multifunctional epicardial device improves cardiac function and tissue repair

S Huang, D Lei, Q Yang, Y Yang, C Jiang, H Shi… - Nature medicine, 2021 - nature.com
Despite advances in technologies for cardiac repair after myocardial infarction (MI), new
integrated therapeutic approaches still need to be developed. In this study, we designed a …

[HTML][HTML] Biodegradable scaffolds for bone regeneration combined with drug-delivery systems in osteomyelitis therapy

R Dorati, A DeTrizio, T Modena, B Conti, F Benazzo… - Pharmaceuticals, 2017 - mdpi.com
A great deal of research is ongoing in the area of tissue engineering (TE) for bone
regeneration. A possible improvement in restoring damaged tissues involves the loading of …

Minimally invasive and regenerative therapeutics

N Ashammakhi, S Ahadian, MA Darabi… - Advanced …, 2019 - Wiley Online Library
Advances in biomaterial synthesis and fabrication, stem cell biology, bioimaging,
microsurgery procedures, and microscale technologies have made minimally invasive …

Materials science and design principles of growth factor delivery systems in tissue engineering and regenerative medicine

R Subbiah, RE Guldberg - Advanced healthcare materials, 2019 - Wiley Online Library
Growth factors (GFs) are signaling molecules that direct cell development by providing
biochemical cues for stem cell proliferation, migration, and differentiation. GFs play a key …

Controlled drug release for tissue engineering

KJ Rambhia, PX Ma - Journal of Controlled Release, 2015 - Elsevier
Tissue engineering is often referred to as a three-pronged discipline, with each prong
corresponding to 1) a 3D material matrix (scaffold), 2) drugs that act on molecular signaling …

[HTML][HTML] Release of VEGF and BMP9 from injectable alginate based composite hydrogel for treatment of myocardial infarction

Y Wu, T Chang, W Chen, X Wang, J Li, Y Chen, Y Yu… - Bioactive materials, 2021 - Elsevier
Myocardial infarction (MI) is one of cardiovascular diseases that pose a serious threat to
human health. The pathophysiology of MI is complex and contains several sequential …

Glycosaminoglycan‐based biohybrid hydrogels: a sweet and smart choice for multifunctional biomaterials

U Freudenberg, Y Liang, KL Kiick… - Advanced …, 2016 - Wiley Online Library
Glycosaminoglycans (GAGs) govern important functional characteristics of the extracellular
matrix (ECM) in living tissues. Incorporation of GAGs into biomaterials opens up new routes …