The emerging roles and clinical potential of circSMARCA5 in cancer

C Xue, J Wei, M Li, S Chen, L Zheng, Y Zhan, Y Duan… - Cells, 2022 - mdpi.com
Circular RNAs (circRNAs) are a type of endogenous non-coding RNA and a critical
epigenetic regulation way that have a closed-loop structure and are highly stable …

The relationship between cancer and biomechanics

L Bao, H Kong, Y Ja, C Wang, L Qin, H Sun… - Frontiers in …, 2023 - frontiersin.org
The onset, development, diagnosis, and treatment of cancer involve intricate interactions
among various factors, spanning the realms of mechanics, physics, chemistry, and biology …

Nm23‐H1 inhibits lung cancer bone‐specific metastasis by upregulating miR‐660‐5p targeted SMARCA5

C Ai, G Ma, Y Deng, Q Zheng, Y Gen, W Li, Y Li… - Thoracic …, 2020 - Wiley Online Library
Background Nm23‐H1 gene has been found to be an inhibitor of tumor metastasis in lung
cancer. MicroRNAs (miRNAs) play key roles in tumor metastasis through multiple signaling …

Intratumoral restoration of miR-137 plus cholesterol favors homeostasis of the miR-137/coactivator p160/AR axis and negatively modulates tumor progression in …

R Pimenta, CM Mioshi, GL Gonçalves… - International journal of …, 2023 - mdpi.com
MicroRNAs (miRNAs) have gained a prominent role as biomarkers in prostate cancer (PCa).
Our study aimed to evaluate the potential suppressive effect of miR-137 in a model of …

Overexpression of SMARCA5 correlates with cell proliferation and migration in breast cancer

Q Jin, X Mao, B Li, S Guan, F Yao, F Jin - Tumor Biology, 2015 - Springer
SMARCA5 partners with RSF-1 to compose the RSF complex, which belongs to the ISWI
family of chromatin remodelers. Recent studies referred that SMARCA5 was overexpressed …

Ras and Wnt interaction contribute in prostate cancer bone metastasis

SR Lin, N Mokgautsi, YN Liu - Molecules, 2020 - mdpi.com
Prostate cancer (PCa) is one of the most prevalent and malignant cancer types in men,
which causes more than three-hundred thousand cancer death each year. At late stage of …

MicroRNA in prostate cancer

K Khanmi, S Ignacimuthu, MG Paulraj - Clinica chimica acta, 2015 - Elsevier
Abstract In the United States of America male prostate cancer (PCa) is the most dominant
malignancy and the second highest cause of cancer-related mortality risk compared to lung …

Differentially expressed genes and signature pathways of human prostate cancer

JS Myers, AK von Lersner, CJ Robbins, QXA Sang - PloS one, 2015 - journals.plos.org
Genomic technologies including microarrays and next-generation sequencing have enabled
the generation of molecular signatures of prostate cancer. Lists of differentially expressed …

Loss of ISWI ATPase SMARCA5 (SNF2H) in acute myeloid leukemia cells inhibits proliferation and chromatid cohesion

T Zikmund, H Paszekova, J Kokavec, P Kerbs… - International journal of …, 2020 - mdpi.com
ISWI chromatin remodeling ATPase SMARCA5 (SNF2H) is a well-known factor for its role in
regulation of DNA access via nucleosome sliding and assembly. SMARCA5 transcriptionally …

MicroRNA-100 regulates pancreatic cancer cells growth and sensitivity to chemotherapy through targeting FGFR3

Z Li, X Li, C Yu, M Wang, F Peng, J Xiao, R Tian… - Tumor Biology, 2014 - Springer
We intended to investigate the role of microRNA 100 (miR-100) in regulating pancreatic
cancer cells' growth in vitro and tumor development in vivo. QTR-PCR was used to examine …