RNA structure is crucial for gene regulation and function. In the past, transcriptomes have
largely been parsed by primary sequences and expression levels, but it is now becoming …

RNA binding proteins (RBPs) play a central role in mediating post transcriptional regulation
of genes. However less is understood about them and their regulatory mechanisms. In this …

Transcript function is determined by sequence elements arranged on an individual RNA
molecule. Variation in transcripts can affect messenger RNA stability, localization and …

Cellular responses to environmental stress are frequently mediated by RNA-binding
proteins (RBPs). Here, we examined global RBP dynamics in Saccharomyces cerevisiae in …

Cellular matter can be organized into compositionally distinct biomolecular condensates.
For example, in Ashbya gossypii, the RNA-binding protein Whi3 forms distinct condensates …

Biogenesis of eukaryotic messenger ribonucleoprotein complexes (mRNPs) involves the
synthesis, splicing, and 3′ processing of pre-mRNA, and the assembly of mature mRNPs …

Transcriptomics experiments and computational predictions both enable systematic
discovery of new functional RNAs. However, many putative noncoding transcripts arise …

RNA–protein interactions differ from DNA–protein interactions because of the central role of
RNA secondary structure. Some RNA‐binding domains (RBDs) recognize their target sites …

Recent research has uncovered extensive variability in the boundaries of transcript isoforms,
yet the functional consequences of this variation remain largely unexplored. Here, we …

Autophagy is an essential eukaryotic pathway requiring tight regulation to maintain
homeostasis and preclude disease. Using yeast and mammalian cells, we report a …