The oligometastatic spectrum in the era of improved detection and modern systemic therapy

RR Katipally, SP Pitroda, A Juloori… - Nature Reviews …, 2022 - nature.com
Metastases remain the leading cause of cancer-related mortality. The oligometastasis
hypothesis postulates that a spectrum of metastatic spread exists and that some patients …

Emerging evidence and treatment paradigm of non-small cell lung cancer

SYM Liu, MM Zheng, Y Pan, SY Liu, Y Li… - Journal of hematology & …, 2023 - Springer
Research on biomarker-driven therapy and immune check-point blockade in non-small cell
lung cancer (NSCLC) is rapidly evolving. The width and depth of clinical trials have also …

Oncogene-addicted metastatic non-small-cell lung cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up☆

LE Hendriks, KM Kerr, J Menis, TS Mok… - Annals of …, 2023 - annalsofoncology.org
Details on diagnostic procedures are covered in the Supplementary Material Section 2,
available at https://doi. org/10.1016/j. annonc. 2022.12. 009. See Supplementary Figure S1 …

Early Clearance of Plasma Epidermal Growth Factor Receptor Mutations as a Predictor of Outcome on Osimertinib in Advanced Non–Small Cell Lung Cancer; …

JE Gray, MJ Ahn, GR Oxnard, FA Shepherd… - Clinical cancer …, 2023 - AACR
Purpose: Plasma circulating tumor DNA (ctDNA) analysis is used for genotyping advanced
non–small cell lung cancer (NSCLC); monitoring dynamic ctDNA changes may be used to …

[HTML][HTML] Stereotactic body radiation therapy for spinal metastases: Benefits and limitations

M Guckenberger, M Dahele, WL Ong… - Seminars in radiation …, 2023 - Elsevier
Progress in biological cancer characterization, targeted systemic therapies and
multimodality treatment strategies have shifted the goals of radiotherapy for spinal …

Oligometastases: emerging evidence

W Liu, H Bahig, DA Palma - Journal of Clinical Oncology, 2022 - ascopubs.org
The hypothesis that ablative therapies (such as surgery or radiation) can be used to cure
patients with a limited number of metastases was influential in changing practice. Early …

Systemic therapy with or without local intervention for oligometastatic oesophageal squamous cell carcinoma (ESO-Shanghai 13): an open-label, randomised, phase …

Q Liu, J Chen, Y Lin, J Ye, W Shen, H Luo… - The Lancet …, 2024 - thelancet.com
Background The efficacy of local therapy for patients with oligometastatic oesophageal
squamous cell carcinoma is unclear. We aimed to assess the efficacy of local plus systemic …

Combining stereotactic body radiotherapy with immunotherapy in stage IV non-small cell lung cancer

X Liu, A Chi - Frontiers in Oncology, 2023 - frontiersin.org
Immunotherapy has revolutionized the treatment of metastatic non-small cell lung cancer
(NSCLC). Oligometastasis has been associated with better prognosis than widespread …

[HTML][HTML] International consensus on radiotherapy in metastatic non-small cell lung cancer

Z Zhu, J Ni, X Cai, S Su, H Zhuang, Z Yang… - Translational Lung …, 2022 - ncbi.nlm.nih.gov
Background Lung cancer is the leading cause of cancer-related death worldwide, with non-
small cell lung cancer (NSCLC) accounting for most cases. While radiotherapy has …

Oligo-metastatic cancers: putative biomarkers, emerging challenges and new perspectives

A Ottaiano, M Santorsola, L Circelli, AM Trotta, F Izzo… - Cancers, 2023 - mdpi.com
Simple Summary Oligometastatic disease is a condition in oncology where cancer affects
only a few distant sites. It is associated with a low-burden spread and a more favorable …