[HTML][HTML] Micro-and nanoplastics: a new cardiovascular risk factor?

X Zhu, C Wang, X Duan, B Liang, EG Xu… - Environment international, 2023 - Elsevier
Exposure to micro-and nanoplastics (MNPs) is inevitable due to their omnipresence in the
environment. A growing body of studies has advanced our understanding of the potential …

NLRP3 inflammasome: Its regulation and involvement in atherosclerosis

Z Hoseini, F Sepahvand, B Rashidi… - Journal of cellular …, 2018 - Wiley Online Library
Inflammasomes are intracellular complexes involved in the innate immunity that convert
proIL‐1β and proIL‐18 to mature forms and initiate pyroptosis via cleaving procaspase‐1 …

Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis

X Wu, H Zhang, W Qi, Y Zhang, J Li, Z Li, Y Lin… - Cell death & …, 2018 - nature.com
Cigarette smoking is a major risk factor for atherosclerosis and other cardiovascular
diseases. Increasing evidence has demonstrated that nicotine impairs the cardiovascular …

Melatonin prevents endothelial cell pyroptosis via regulation of long noncoding RNA MEG3/miR‐223/NLRP3 axis

Y Zhang, X Liu, X Bai, Y Lin, Z Li, J Fu… - Journal of pineal …, 2018 - Wiley Online Library
Atherosclerosis (AS) is an inflammatory disease linked to endothelial dysfunction. Melatonin
is reported to possess substantial anti‐inflammatory properties, which has proven to be …

NLRP3 inflammasome activation‐mediated pyroptosis aggravates myocardial ischemia/reperfusion injury in diabetic rats

Z Qiu, S Lei, B Zhao, Y Wu, W Su, M Liu… - Oxidative medicine …, 2017 - Wiley Online Library
The reactive oxygen species‐(ROS‐) induced nod‐like receptor protein‐3 (NLRP3)
inflammasome triggers sterile inflammatory responses and pyroptosis, which is a …

Pyroptosis and its relationship to atherosclerosis

YJ Xu, L Zheng, YW Hu, Q Wang - Clinica Chimica Acta, 2018 - Elsevier
Pyroptosis is a pro-inflammatory form of regulated cell death and is dependent on the
enzymatic activity of inflammatory proteases that belong to the family of cysteine-dependent …

Role of pyroptosis in cardiovascular diseases

C Jia, H Chen, J Zhang, K Zhou, Y Zhuge, C Niu… - International …, 2019 - Elsevier
Pyroptosis is a form of programmed necrosis, and is morphologically and mechanistically
unique form of programmed cell death compared to others, such as apoptosis and …

Coronary atherosclerotic vulnerable plaque: current perspectives

C Stefanadis, CK Antoniou, D Tsiachris… - Journal of the American …, 2017 - Am Heart Assoc
Atherosclerosis is the most common form of vascular disease and constitutes the major
cause of death, with 17.5 million related deaths annually (31% of global mortality). 1 …

Pyroptosis in the initiation and progression of atherosclerosis

Z Qian, Y Zhao, C Wan, Y Deng, Y Zhuang… - Frontiers in …, 2021 - frontiersin.org
Pyroptosis, a newly discovered form of programmed cell death, is characterized by cell
swelling, the protrusion of large bubbles from the plasma membrane and cell lysis. This …

The impact of polystyrene microplastics on cardiomyocytes pyroptosis through NLRP3/Caspase‐1 signaling pathway and oxidative stress in Wistar rats

J Wei, X Wang, Q Liu, N Zhou, S Zhu, Z Li… - Environmental …, 2021 - Wiley Online Library
The extensive existing of microplastics (MPs) in the ecosystem have increased considerable
attention concerning their potential adverse effects, the toxicities and the underlying …