DNA methylation: superior or subordinate in the epigenetic hierarchy?

B Jin, Y Li, KD Robertson - Genes & cancer, 2011 - journals.sagepub.com
Epigenetic modifications are heritable changes in gene expression not encoded by the DNA
sequence. In the past decade, great strides have been made in characterizing epigenetic …

Effect of Freeze‐Drying on Apple Pomace and Pomegranate Peel Powders Used as a Source of Bioactive Ingredients for the Development of Functional Yogurt

M Ahmed, A Ali, A Sarfraz, Q Hong… - Journal of Food …, 2022 - Wiley Online Library
Agro‐industrial by‐products of fruits have turned into an essential source of bioactive
products. This study examined the effect of freeze‐drying on apple pomace powder (APP) …

5-hmC–mediated epigenetic dynamics during postnatal neurodevelopment and aging

KE Szulwach, X Li, Y Li, CX Song, H Wu, Q Dai… - Nature …, 2011 - nature.com
DNA methylation dynamics influence brain function and are altered in neurological
disorders. 5-hydroxymethylcytosine (5-hmC), a DNA base that is derived from 5 …

Retinoic acid receptors: from molecular mechanisms to cancer therapy

A Di Masi, L Leboffe, E De Marinis, F Pagano… - Molecular aspects of …, 2015 - Elsevier
Retinoic acid (RA), the major bioactive metabolite of retinol or vitamin A, induces a spectrum
of pleiotropic effects in cell growth and differentiation that are relevant for embryonic …

Bump hunting to identify differentially methylated regions in epigenetic epidemiology studies

AE Jaffe, P Murakami, H Lee, JT Leek… - International journal …, 2012 - academic.oup.com
Background During the past 5 years, high-throughput technologies have been successfully
used by epidemiology studies, but almost all have focused on sequence variation through …

From profiles to function in epigenomics

SH Stricker, A Köferle, S Beck - Nature Reviews Genetics, 2017 - nature.com
Myriads of epigenomic features have been comprehensively profiled in health and disease
across cell types, tissues and individuals. Although current epigenomic approaches can …

Structural insight into autoinhibition and histone H3-induced activation of DNMT3A

X Guo, L Wang, J Li, Z Ding, J Xiao, X Yin, S He, P Shi… - Nature, 2015 - nature.com
DNA methylation is an important epigenetic modification that is essential for various
developmental processes through regulating gene expression, genomic imprinting, and …

Persistent epigenetic differences associated with prenatal exposure to famine in humans

BT Heijmans, EW Tobi, AD Stein… - Proceedings of the …, 2008 - National Acad Sciences
Extensive epidemiologic studies have suggested that adult disease risk is associated with
adverse environmental conditions early in development. Although the mechanisms behind …

[图书][B] Organism and environment: ecological development, niche construction, and adaptation

SE Sultan - 2015 - books.google.com
Over the past decade, advances in both molecular developmental biology and evolutionary
ecology have made possible a new understanding of organisms as dynamic systems …

Active DNA demethylation: many roads lead to Rome

SC Wu, Y Zhang - Nature reviews Molecular cell biology, 2010 - nature.com
DNA methylation is one of the best-characterized epigenetic modifications and has been
implicated in numerous biological processes, including transposable element silencing …