Chronic obstructive pulmonary disease (COPD) is a type of obstructive lung disease
characterized by long-term breathing problems and poor airflow. Exhaled breath …

Background Smoking cessation is the best possible way to prevent the progression of
smoking related airway diseases. However, the effect and time scale of smoking cessation …

Background. Elastase mediates important oxidative actions during the development of
chronic obstructive pulmonary disease (COPD). However, few resources for the inhibition of …

Background and objective Inflammation is present to a variable degree and composition in
patients with COPD. This study investigates associations between both eosinophils and …

Asthma is a heterogeneous disease with varying phenotypes and numerous risk factors.
This condition results from complex interactions between genetic and environmental factors …

Background In asthma, higher chymase positive mast cell (MC-C) numbers are associated
with less airway obstruction. In COPD, the distribution of MC-C and tryptase positive mast …

The coexistence of upper airways disease with chronic obstructive pulmonary disease
(COPD) is not well documented. The aim of this research was to assess sino-nasal …

Background and Purpose A critical role for sphingosine kinase/sphingosine‐1‐phosphate
(S1P) pathway in the control of airway function has been demonstrated in respiratory …

Introduction: Many theories have been proposed to explain pathogenesis of COPD;
however, remains unclear why the majority of smokers (~ 80%) do not develop COPD, or …

In the United States, there are almost 4 million smokers older than 65. Yet, older smokers
often receive suboptimal care. Inaccurate information and myths about older smokers may …