In the United States, there are almost 4 million smokers older than 65. Yet, older smokers
often receive suboptimal care. Inaccurate information and myths about older smokers may …

Once COPD is established, pulmonary lesions can only progress and smoking cessation by
itself is not sufficient to switch off persistent lung inflammation. Similarly, in former-smoker …

Accurate cervical intra-epithelial neoplasia (CIN) lesion grading is needed for effective
patient management. We applied computer-assisted scanning and analytic approaches to …

Smoking is a potent cause of asthma exacerbations, chronic obstructive pulmonary disease
(COPD) and many other health defects, and changes in DNA methylation (DNAm) have …

Background Histone deacetylase (HDAC) is an enzyme that regulates chromatin structure
and inflammatory gene expression. In patients with chronic obstructive pulmonary disease …

BACKGROUND: In COPD, although histological lesions at both the small airways (wall
thickening and tissue remodeling) and lung parenchyma (emphysematous destruction) are …

There is intense scientific and clinical interest in chronic obstructive pulmonary disease
(COPD), which is reflected in the increasing number of articles in scientific journals on this …

Background Chronic obstructive pulmonary disease (COPD) is the 4 th leading cause of
mortality worldwide. Long-acting bronchodilators are considered first line therapies for …

Endogenous airway acidification, as assessed by exhaled breath condensate (EBC) pH, is
present in patients with stable COPD. The aim of this study was to measure EBC pH levels in …

Chronic obstructive pulmonary disease (COPD) has been defined as a preventable and
treatable disease characterised by progressive airflow limitation that is not fully reversible …