miR-199a: a tumor suppressor with noncoding rna network and therapeutic candidate in lung cancer
W Meng, Y Li, B Chai, X Liu, Z Ma - International journal of molecular …, 2022 - mdpi.com
Lung cancer is the leading cause of cancer death worldwide. miR-199a, which has two
mature molecules: miR-199a-3p and miR-199a-5p, plays an important biological role in the …
mature molecules: miR-199a-3p and miR-199a-5p, plays an important biological role in the …
Liquid biopsy analysis as a tool for TKI-Based treatment in non-small cell lung cancer
K Buszka, A Ntzifa, B Owecka, P Kamińska… - Cells, 2022 - mdpi.com
The treatment of non-small cell lung cancer (NSCLC) has recently evolved with the
introduction of targeted therapy based on the use of tyrosine kinase inhibitors (TKIs) in …
introduction of targeted therapy based on the use of tyrosine kinase inhibitors (TKIs) in …
[HTML][HTML] Inhibition of DCLK1 sensitizes resistant lung adenocarcinomas to EGFR-TKI through suppression of Wnt/β-Catenin activity and cancer stemness
R Yan, X Fan, Z Xiao, H Liu, X Huang, J Liu, S Zhang… - Cancer letters, 2022 - Elsevier
Lung adenocarcinoma is the most common form of lung cancer, accounting for 60% of non-
small cell lung cancer (NSCLC) cases in Asian patients. Importantly, nearly half of these …
small cell lung cancer (NSCLC) cases in Asian patients. Importantly, nearly half of these …
Exosomes derived from M2 type tumor-associated macrophages promote osimertinib resistance in non-small cell lung cancer through MSTRG. 292666.16-miR-6836 …
X Wan, B Xie, H Sun, W Gu, C Wang, Q Deng… - Cancer cell …, 2022 - Springer
Background Osimertinib resistance limits the treatment of epidermal growth factor receptor-
(EGFR)-mutated non-small-cell lung carcinoma (NSCLC). The mechanisms of osimertinib …
(EGFR)-mutated non-small-cell lung carcinoma (NSCLC). The mechanisms of osimertinib …
[HTML][HTML] Development of a QCM-based biosensor for the detection of non-small cell lung cancer biomarkers in liquid biopsies
Lung cancer is the main malignant cancer reported worldwide, with one of the lowest
survival rates. Deletions in the Epidermal Growth Factor Receptor (EGFR) gene are often …
survival rates. Deletions in the Epidermal Growth Factor Receptor (EGFR) gene are often …
Azithromycin enhances the cytotoxicity of DNA‐damaging drugs via lysosomal membrane permeabilization in lung cancer cells
K Toriyama, N Takano, H Kokuba, H Kazama… - Cancer …, 2021 - Wiley Online Library
Cancer cells use autophagy for growth, survival, and cytoprotection from chemotherapy.
Therefore, autophagy inhibitors appear to be good candidates for cancer treatment. Our …
Therefore, autophagy inhibitors appear to be good candidates for cancer treatment. Our …
Identification of a Pyroptosis‐Related Gene Signature for Prediction of Overall Survival in Lung Adenocarcinoma
Z Dong, L Bian, M Wang, L Wang… - Journal of Oncology, 2021 - Wiley Online Library
Pyroptosis is a kind of programmed cell death that is characterized by inflammation.
However, the expression of pyroptosis‐related genes and their connection with prognosis in …
However, the expression of pyroptosis‐related genes and their connection with prognosis in …
Arsenic inhibits proliferation and induces autophagy of tumor cells in pleural effusion of patients with non-small cell lung cancer expressing EGFR with or without …
J Mao, X Shi, L Hua, M Yang, Y Shen, Z Ruan, B Li… - Biomedicines, 2023 - mdpi.com
To clarify whether arsenic could exert inhibitory effects on tumor cells in pleural effusions of
patients with non-small cell lung cancer (NSCLC), 36 NSCLC pleural effusion samples were …
patients with non-small cell lung cancer (NSCLC), 36 NSCLC pleural effusion samples were …
Identification of a four-gene signature associated with the prognosis prediction of lung adenocarcinoma based on integrated bioinformatics analysis
Y Wu, L Yang, L Zhang, X Zheng, H Xu, K Wang… - Genes, 2022 - mdpi.com
Lung adenocarcinoma (LUAD) is often diagnosed at an advanced stage, so it is necessary
to identify potential biomarkers for the early diagnosis and prognosis of LUAD. In our study …
to identify potential biomarkers for the early diagnosis and prognosis of LUAD. In our study …
Recent application of artificial intelligence on histopathologic image-based prediction of gene mutation in solid cancers
Purpose Evaluation of genetic mutations in cancers is important because distinct mutational
profiles help determine individualized drug therapy. However, molecular analyses are not …
profiles help determine individualized drug therapy. However, molecular analyses are not …