Nuclear factor-kappa B, involved in inflammation, host immune response, cell adhesion,
growth signals, cell proliferation, cell differentiation, and apoptosis defense, is a dimeric …

Colorectal cancer (CRC) represents the second leading cause of cancer-related deaths
worldwide. The pathogenesis of CRC is a complex multistep process. Among other factors …

Acute lung injury (ALI) is a pulmonary disorder, which can result in fibrosis of the lung
tissues. Recently, mesenchymal stem cell (MSC) has become a novel therapeutic method …

Abstract Type-1 and type-3 interferons (IFNs) are important for control of viral replication;
however, less is known about the role of Type-2 IFN (IFNγ) in anti-viral immunity. We …

The chemokine receptor CXCR2 and its ligands are implicated in the progression of tumours
and various inflammatory diseases. Activation of the CXCLs/CXCR2 axis activates multiple …

The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

Background Lactoferrin, a normal component of human colostrum and milk, can enhance
host defenses and may be effective for prevention of sepsis and necrotizing enterocolitis …

Skin areas exposed to ultraviolet radiation (UV) from sunlight are more prone to photoaging
than unexposed areas evidenced by several signs which include skin dryness, irregular …

Nanoscale objects, whether of biologic origin or synthetically created, are being developed
into devices for a variety of bionanotechnology diagnostic and pharmaceutical applications …

EC activation and dysfunction have been linked to a variety of vascular inflammatory
disease states. The function of microRNAs (miRNAs) in vascular EC activation and …