Biology and therapeutic targeting of vascular endothelial growth factor A
L Pérez-Gutiérrez, N Ferrara - Nature Reviews Molecular Cell Biology, 2023 - nature.com
The formation of new blood vessels, called angiogenesis, is an essential pathophysiological
process in which several families of regulators have been implicated. Among these, vascular …
process in which several families of regulators have been implicated. Among these, vascular …
[HTML][HTML] Angiogenic signaling pathways and anti-angiogenic therapy for cancer
ZL Liu, HH Chen, LL Zheng, LP Sun… - Signal transduction and …, 2023 - nature.com
Angiogenesis, the formation of new blood vessels, is a complex and dynamic process
regulated by various pro-and anti-angiogenic molecules, which plays a crucial role in tumor …
regulated by various pro-and anti-angiogenic molecules, which plays a crucial role in tumor …
Absorption, distribution, metabolism, excretion and toxicity of microplastics in the human body and health implications
Abstract Microplastics (MPs;< 5 mm) in the biosphere draws public concern about their
potential health impacts. Humans are potentially exposed to MPs via ingestion, inhalation …
potential health impacts. Humans are potentially exposed to MPs via ingestion, inhalation …
[HTML][HTML] Vascular mechanobiology: homeostasis, adaptation, and disease
JD Humphrey, MA Schwartz - Annual review of biomedical …, 2021 - annualreviews.org
Cells of the vascular wall are exquisitely sensitive to changes in their mechanical
environment. In healthy vessels, mechanical forces regulate signaling and gene expression …
environment. In healthy vessels, mechanical forces regulate signaling and gene expression …
Tumor targeting via EPR: Strategies to enhance patient responses
The tumor accumulation of nanomedicines relies on the enhanced permeability and
retention (EPR) effect. In the last 5–10 years, it has been increasingly recognized that there …
retention (EPR) effect. In the last 5–10 years, it has been increasingly recognized that there …
[HTML][HTML] Oxidative stress in preeclampsia and placental diseases
R Aouache, L Biquard, D Vaiman… - International journal of …, 2018 - mdpi.com
Preeclampsia is a persistent hypertensive gestational disease characterized by high blood
pressure and proteinuria, which presents from the second trimester of pregnancy. At the …
pressure and proteinuria, which presents from the second trimester of pregnancy. At the …
[HTML][HTML] Contribution of angiogenesis to inflammation and cancer
D Aguilar-Cazares, R Chavez-Dominguez… - Frontiers in …, 2019 - frontiersin.org
During carcinogenesis, advanced tumors are surrounded by both stromal and immune cells,
which support tumor development. In addition, inflammation and angiogenesis are …
which support tumor development. In addition, inflammation and angiogenesis are …
Recent trends and advances in fundus image analysis: A review
Automated retinal image analysis holds prime significance in the accurate diagnosis of
various critical eye diseases that include diabetic retinopathy (DR), age-related macular …
various critical eye diseases that include diabetic retinopathy (DR), age-related macular …
[HTML][HTML] Impact of metabolic syndrome on neuroinflammation and the blood–brain barrier
P Van Dyken, B Lacoste - Frontiers in neuroscience, 2018 - frontiersin.org
Metabolic syndrome, which includes diabetes and obesity, is one of the most widespread
medical conditions. It induces systemic inflammation, causing far reaching effects on the …
medical conditions. It induces systemic inflammation, causing far reaching effects on the …
[HTML][HTML] Vascular permeability in diseases
JL Wautier, MP Wautier - International Journal of Molecular Sciences, 2022 - mdpi.com
Vascular permeability is a selective mechanism that maintains the exchange between
vessels, tissues, and organs. The regulation was mostly studied during the nineteenth …
vessels, tissues, and organs. The regulation was mostly studied during the nineteenth …