Acute Liver Failure | New England Journal of Medicine Skip to main content The New England
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Acute liver failure is a rare and severe consequence of abrupt hepatocyte injury, and can
evolve over days or weeks to a lethal outcome. A variety of insults to liver cells result in a …

Abbreviations: AASLD, American Association for the Study of Liver Diseases; AIH,
autoimmune hepatitis; ALF, acute liver failure; ALT, alanine aminotransferase; AMA …

The first human orthotopic liver transplantation (LT) in Europe was performed by Sir Roy
Calne in Cambridge in 1968 [1], only one year after the first successful human liver …

The term acute liver failure (ALF) is frequently applied as a generic expression to describe
patients presenting with or developing an acute episode of liver dysfunction. In the context of …

Autoimmune hepatitis (AIH) was the first liver disease for which an effective therapeutic
intervention, corticosteroid treatment, was convincingly demonstrated in controlled clinical …

Paediatric autoimmune liver disease is characterized by inflammatory liver histology,
circulating autoantibodies, and increased levels of IgG, in the absence of a known etiology …

Liver disease is the twelfth commonest cause of mortality in adults in the United States,
resulting in 34,000 deaths annually from cirrhosis. 7 In addition, the rising incidence of HCC …

Idiosyncratic drug-induced liver injury (DILI) is a rare adverse drug reaction and it can lead
to jaundice, liver failure, or even death. Antimicrobials and herbal and dietary supplements …

Clinical practice guidelines are defined as ''systematically developed statements to assist
practitioner and patient decisions about appropriate heath care for specific clinical …