Nitric oxide (NO) is a pleiotropic janus-faced molecule synthesized by nitric oxide synthases
(NOS) which plays a critical role in a number of physiological and pathological processes in …

CXCL12 is a CXC chemokine that traditionally has been classified as a homeostatic
chemokine. It contributes to physiological processes such as embryogenesis, hematopoiesis …

Multiple sclerosis is a neurologic disease caused by immune cell infiltration into the central
nervous system, resulting in gray and white matter inflammation, progressive demyelination …

The pathophysiology of different neurodegenerative illnesses is significantly influenced by
the polarization regulation of microglia and macrophages. Traditional classifications of …

Background The mechanisms underlying the pathogenesis and progression of Parkinson's
disease (PD) remain elusive, but recent opinions and perspectives have focused on whether …

Over the last decades, nitric oxide (NO) has been definitively recognised as one of the key
players involved in immunity and inflammation. NO generation was originally described in …

Gasotransmitters are a group of gaseous molecules, with pleiotropic biological functions.
These molecules include nitric oxide (NO), hydrogen sulfide (H 2 S), and carbon monoxide …

Multiple sclerosis (MS) as a chronic inflammatory disorder of the central nervous system
(CNS) is thought to be caused by the abnormal induction of immune responses …

Ischemic cerebral stroke is one of the leading global causes of mortality and morbidity.
Ischemic preconditioning (IPC) refers to a sublethal ischemia and resulting in tolerance to …

The chemokine CXCL12/stromal cell-derived factor-1 is important for leukocyte migration to
lymphoid organs and inflamed tissues and stimulates tumor development. In vitro, CXCL12 …