The homeodomain transcription factor Nkx2-1 plays key roles in the developing
telencephalon, where it regulates the identity of progenitor cells in the medial ganglionic …

Little is known of the intracellular machinery that controls the motility of newborn neurons.
We have previously shown that the proneural protein Neurog2 promotes the migration of …

Summary Nedd4-1 is a" neuronal precursor cell expressed and developmentally
downregulated protein" and among the most abundant E3 ubiquitin ligases in mammalian …

Motility is a universal property of newly generated neurons. How cell migration is
coordinately regulated with other aspects of neuron production is not well understood. Here …

The ability of neurons to form a single axon and multiple dendrites underlies the directional
flow of information transfer in the central nervous system. Dendrites and axons are …

Although dendrite arborization patterns are hallmarks of neuronal type and critical
determinants of neuronal function, how dendritic arbors take shape is still largely unknown …

Cranial placodes (which include the adenohypophyseal, olfactory, lens, otic, lateral line,
profundal/trigeminal, and epibranchial placodes) give rise to many sense organs and …

Postmitotic neurons in the developing cortex migrate along radial glial fibers to their proper
location in the cortical plate and form the layered structure. Here we report that the radial …

Neurons begin their life as simple spheres, but can ultimately assume an elaborate
morphology with numerous, highly arborized dendrites, and long axons. This is achieved via …

Mammalian cortical development involves neuronal migration and neuritogenesis; this latter
process forms the structural precursors to axons and dendrites. Elucidating the pathways …