The future of organ perfusion and re‐conditioning
A Weissenbacher, G Vrakas, D Nasralla… - Transplant …, 2019 - Wiley Online Library
Organ preservation and re‐conditioning using machine perfusion technologies continue to
generate promising results in terms of viability assessment, organ utilization and improved …
generate promising results in terms of viability assessment, organ utilization and improved …
[HTML][HTML] Renal normothermic machine perfusion: the road toward clinical implementation of a promising pretransplant organ assessment tool
TL Hamelink, B Ogurlu, J De Beule, VA Lantinga… - …, 2022 - journals.lww.com
The increased utilization of high-risk renal grafts for transplantation requires optimization of
pretransplant organ assessment strategies. Current decision-making methods to accept an …
pretransplant organ assessment strategies. Current decision-making methods to accept an …
Normothermic machine perfusion for the assessment and transplantation of declined human kidneys from donation after circulatory death donors
SA Hosgood, E Thompson, T Moore… - Journal of British …, 2018 - academic.oup.com
Background A significant proportion of donation after circulatory death (DCD) kidneys are
declined for transplantation because of concerns over their quality. Ex vivo normothermic …
declined for transplantation because of concerns over their quality. Ex vivo normothermic …
[HTML][HTML] Twenty-four–hour normothermic perfusion of discarded human kidneys with urine recirculation
A Weissenbacher, LL Faro, O Boubriak… - American Journal of …, 2019 - Elsevier
Transportable normothermic kidney perfusion for 24 hours or longer could enable viability
assessment of marginal grafts, increased organ use, and improved transplant logistics …
assessment of marginal grafts, increased organ use, and improved transplant logistics …
[HTML][HTML] Past, present, and future of dynamic kidney and liver preservation and resuscitation
I Jochmans, MZ Akhtar, D Nasralla… - American Journal of …, 2016 - Elsevier
The increased demand for organs has led to the increased usage of “higher risk” kidney and
liver grafts. These grafts from donation after circulatory death or expanded criteria donors …
liver grafts. These grafts from donation after circulatory death or expanded criteria donors …
Successful Transplantation of Human Kidneys Deemed Untransplantable but Resuscitated by Ex Vivo Normothermic Machine Perfusion
SA Hosgood, K Saeb‐Parsy, MO Hamed… - American Journal of …, 2016 - Wiley Online Library
We report the successful transplantation of a pair of human kidneys that were declined for
transplantation due to inadequate in situ perfusion but subsequently transplanted after …
transplantation due to inadequate in situ perfusion but subsequently transplanted after …
[HTML][HTML] Normothermic ex vivo kidney perfusion for graft quality assessment prior to transplantation
JM Kaths, M Hamar, J Echeverri, I Linares… - American Journal of …, 2018 - Elsevier
Normothermic ex vivo kidney perfusion (NEVKP) represents a novel approach for graft
preservation and functional improvement in kidney transplantation. We investigated whether …
preservation and functional improvement in kidney transplantation. We investigated whether …
Extracellular vesicles derived from mesenchymal stromal cells delivered during hypothermic oxygenated machine perfusion repair ischemic/reperfusion damage of …
T Rampino, M Gregorini, G Germinario, EF Pattonieri… - Biology, 2022 - mdpi.com
Simple Summary In this study, we explore for the first time an innovative tool for organ
preservation aimed to preventing ischemia reperfusion injury (IRI) in marginal kidneys from …
preservation aimed to preventing ischemia reperfusion injury (IRI) in marginal kidneys from …
[HTML][HTML] Ex vivo normothermic perfusion induces donor-derived leukocyte mobilization and removal prior to renal transplantation
JP Stone, AL Ball, WR Critchley, T Major… - Kidney International …, 2016 - Elsevier
Introduction Ex vivo normothermic perfusion offers an alternative method of organ
preservation, allowing donor kidneys to be reanimated and evaluated prior to …
preservation, allowing donor kidneys to be reanimated and evaluated prior to …
Short, cool, and well oxygenated–HOPE for kidney transplantation in a rodent model
P Kron, A Schlegel, O de Rougemont… - Annals of …, 2016 - journals.lww.com
Objectives: The aim of this study was to investigate novel and easily applicable preservation
perfusion techniques in kidney grafts obtained from donors after circulatory death (DCD) …
perfusion techniques in kidney grafts obtained from donors after circulatory death (DCD) …