Non-coding RNAs in human health and disease: potential function as biomarkers and therapeutic targets
T Loganathan, GP Doss C - Functional & integrative genomics, 2023 - Springer
Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …
the origin, course of action and treatment of any disease state is essential. A microscopic …
Principles and innovative technologies for decrypting noncoding RNAs: from discovery and functional prediction to clinical application
YM Sun, YQ Chen - Journal of hematology & oncology, 2020 - Springer
Noncoding RNAs (ncRNAs) are a large segment of the transcriptome that do not have
apparent protein-coding roles, but they have been verified to play important roles in diverse …
apparent protein-coding roles, but they have been verified to play important roles in diverse …
mirDIP 4.1—integrative database of human microRNA target predictions
MicroRNAs are important regulators of gene expression, achieved by binding to the gene to
be regulated. Even with modern high-throughput technologies, it is laborious and expensive …
be regulated. Even with modern high-throughput technologies, it is laborious and expensive …
miRTarBase 2016: updates to the experimentally validated miRNA-target interactions database
MicroRNAs (miRNAs) are small non-coding RNAs of approximately 22 nucleotides, which
negatively regulate the gene expression at the post-transcriptional level. This study …
negatively regulate the gene expression at the post-transcriptional level. This study …
2022 updates to the Rat Genome Database: a findable, accessible, interoperable, and reusable (FAIR) resource
M Vedi, JR Smith, G Thomas Hayman, M Tutaj… - Genetics, 2023 - academic.oup.com
Abstract The Rat Genome Database (RGD, https://rgd. mcw. edu) has evolved from simply a
resource for rat genetic markers, maps, and genes, by adding multiple genomic data types …
resource for rat genetic markers, maps, and genes, by adding multiple genomic data types …
GKLOMLI: a link prediction model for inferring miRNA–lncRNA interactions by using Gaussian kernel-based method on network profile and linear optimization …
Background The limited knowledge of miRNA–lncRNA interactions is considered as an
obstruction of revealing the regulatory mechanism. Accumulating evidence on Human …
obstruction of revealing the regulatory mechanism. Accumulating evidence on Human …
miARma-Seq: a comprehensive tool for miRNA, mRNA and circRNA analysis
E Andrés-León, R Núñez-Torres, AM Rojas - Scientific reports, 2016 - nature.com
Large-scale RNAseq has substantially changed the transcriptomics field, as it enables an
unprecedented amount of high resolution data to be acquired. However, the analysis of …
unprecedented amount of high resolution data to be acquired. However, the analysis of …
Exploratory study on microRNA profiles from plasma-derived extracellular vesicles in Alzheimer's disease and dementia with Lewy bodies
A Gámez-Valero, J Campdelacreu, D Vilas… - Translational …, 2019 - Springer
Background Because of the increasing life expectancy in our society, aging-related
neurodegenerative disorders are one of the main issues in global health. Most of these …
neurodegenerative disorders are one of the main issues in global health. Most of these …
miR‐1, miR‐499 and miR‐208 are sensitive markers to diagnose sudden death due to early acute myocardial infarction
E Pinchi, P Frati, M Aromatario… - Journal of cellular …, 2019 - Wiley Online Library
MicroRNAs (miRNAs) are strongly up‐regulated under pathological stress and in a wide
range of diseases. In recent years, miRNAs are under investigation for their potential use as …
range of diseases. In recent years, miRNAs are under investigation for their potential use as …
RNA sequencing and prediction tools for circular RNAs analysis
E López-Jiménez, AM Rojas, E Andrés-León - Circular RNAs: Biogenesis …, 2018 - Springer
Circular RNAs (circRNAs) are noncoding and single-stranded RNA transcripts able to form
covalently circular-closed structures. They are generated through alternative splicing events …
covalently circular-closed structures. They are generated through alternative splicing events …