Improving bioinformatics prediction of microRNA targets by ranks aggregation

A Quillet, C Saad, G Ferry, Y Anouar, N Vergne… - Frontiers in …, 2020 - frontiersin.org
microRNAs are noncoding RNAs which downregulate a large number of target mRNAs and
modulate cell activity. Despite continued progress, bioinformatics prediction of microRNA …

[HTML][HTML] Differential expression of microRNA miR-150-5p in IgA nephropathy as a potential mediator and marker of disease progression

IZA Pawluczyk, A Didangelos, SJ Barbour, L Er… - Kidney international, 2021 - Elsevier
Understanding why certain patients with IgA nephropathy progress to kidney failure while
others maintain normal kidney function remains a major unanswered question. To help …

The impact of dysregulated microRNA biogenesis machinery and microRNA sorting on neurodegenerative diseases

YT Weng, YM Chang, Y Chern - International Journal of Molecular …, 2023 - mdpi.com
MicroRNAs (miRNAs) are 22-nucleotide noncoding RNAs involved in the differentiation,
development, and function of cells in the body by targeting the 3′-untranslated regions …

The connection between MicroRNAs and oral cancer pathogenesis: emerging biomarkers in oral cancer management

C Osan, S Chira, AM Nutu, C Braicu, M Baciut… - Genes, 2021 - mdpi.com
Oral cancer is a common human malignancy that still maintains an elevated mortality rate
despite scientific progress. Tumorigenesis is driven by altered gene expression patterns of …

Review of databases for experimentally validated human microRNA–mRNA interactions

D Kariuki, K Asam, BE Aouizerat, KA Lewis… - Database, 2023 - academic.oup.com
MicroRNAs (miRs) may contribute to disease etiology by influencing gene expression.
Numerous databases are available for miR target prediction and validation, but their …

[HTML][HTML] Plasma MicroRNA profiling of plasmodium falciparum biomass and association with severity of malaria disease

H Gupta, M Rubio, A Sitoe, R Varo… - Emerging infectious …, 2021 - ncbi.nlm.nih.gov
Severe malaria (SM) is a major public health problem in malaria-endemic countries.
Sequestration of Plasmodium falciparum–infected erythrocytes in vital organs and the …

A panel of noncoding RNAs in non–small‐cell lung cancer

A Bagheri, HRK Khorshid, M Tavallaie… - Journal of cellular …, 2019 - Wiley Online Library
Non–small‐lung cancer (NSCLC) is the leading cause of cancer death. Early detection of
NSCLC could pave the way for effective therapies. Analysis of molecular genetic biomarkers …

Novel miRNA-mRNA interactions conserved in essential cancer pathways

E Andrés-León, I Cases, S Alonso, AM Rojas - Scientific reports, 2017 - nature.com
Cancer is a complex disease in which unrestrained cell proliferation results in tumour
development. Extensive research into the molecular mechanisms underlying tumorigenesis …

The regulatory roles of non-coding RNAs in angiogenesis and neovascularization from an epigenetic perspective

IA Hernández-Romero, L Guerra-Calderas… - Frontiers in …, 2019 - frontiersin.org
Angiogenesis is a crucial process for organ morphogenesis and growth during
development, and it is especially relevant during the repair of wounded tissue in adults. It is …

[HTML][HTML] Understanding neurodevelopmental disorders: the promise of regulatory variation in the 3′ UTRome

KA Wanke, P Devanna, SC Vernes - Biological Psychiatry, 2018 - Elsevier
Neurodevelopmental disorders have a strong genetic component, but despite widespread
efforts, the specific genetic factors underlying these disorders remain undefined for a large …