Circulating microRNA203 and its target genes' role in psoriasis pathogenesis

SA Mostafa, MHS Mohammad, WA Negm… - Frontiers in …, 2022 - frontiersin.org
Numerous microRNAs (miRNAs) have been found to have an aberrant expression in the
peripheral blood or psoriasis patients' lesions. Psoriasis was shown to have the abnormal …

[HTML][HTML] MicroRNA deregulation in triple negative breast cancer reveals a role of miR-498 in regulating BRCA1 expression

N Matamala, MT Vargas, R González-Cámpora… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Emerging evidence suggests that BRCA1 pathway contributes to the behavior of sporadic
triple negative breast cancer (TNBC), but little is known about the mechanisms underlying …

PRKCE non-coding variants influence on transcription as well as translation of its gene

K Khan, S Zafar, A Hafeez, Y Badshah, K Shahid… - RNA biology, 2022 - Taylor & Francis
Untranslated regions of the gene play a crucial role in gene expression regulation at mRNA
and protein levels. Mutations at UTRs impact expression by altering transcription factor …

Regulation of miRNAs as new tool for cutaneous vitality lesions demonstration in ligature marks in deaths by hanging

M Neri, M Fabbri, S D'Errico, M Di Paolo, P Frati… - Scientific Reports, 2019 - nature.com
This study aims to demonstrate that the application of miRNA expression in forensic
pathology, in cases of hanging, applying the method on skin samples. The proposed …

[HTML][HTML] Prediction of the miRNA interactome–established methods and upcoming perspectives

M Schäfer, C Ciaudo - Computational and structural biotechnology journal, 2020 - Elsevier
MicroRNAs (miRNAs) are well-studied small noncoding RNAs involved in post-
transcriptional gene regulation in a wide range of organisms, including mammals. Their …

The Rat Genome Database (RGD) facilitates genomic and phenotypic data integration across multiple species for biomedical research

ML Kaldunski, JR Smith, GT Hayman, K Brodie… - Mammalian …, 2022 - Springer
Abstract Model organism research is essential for discovering the mechanisms of human
diseases by defining biologically meaningful gene to disease relationships. The Rat …

[HTML][HTML] Integrative approaches for analysis of mRNA and microRNA high-throughput data

PV Nazarov, S Kreis - Computational and Structural Biotechnology Journal, 2021 - Elsevier
Advanced sequencing technologies such as RNASeq provide the means for production of
massive amounts of data, including transcriptome-wide expression levels of coding RNAs …

Noncoding RNAs databases: current status and trends

V Maracaja-Coutinho, AR Paschoal… - … biology of non-coding …, 2019 - Springer
One of the most important resources for researchers of noncoding RNAs is the information
available in public databases spread over the internet. However, the effective exploration of …

MicroRNA–target cross-talks: Key players in glioblastoma multiforme

EA Toraih, NM Aly, HY Abdallah… - Tumor …, 2017 - journals.sagepub.com
The role of microRNAs in brain cancer is still naive. Some act as oncogene and others as
tumor suppressors. Discovery of efficient biomarkers is mandatory to debate that aggressive …

Small RNA sequencing reveals Dlk1-Dio3 locus-embedded microRNAs as major drivers of ground-state pluripotency

S Moradi, A Sharifi-Zarchi, A Ahmadi… - Stem cell reports, 2017 - cell.com
Ground-state pluripotency is a cell state in which pluripotency is established and maintained
through efficient repression of endogenous differentiation pathways. Self-renewal and …