miR‐200a/b/‐429 downregulation is a candidate biomarker of tumor radioresistance and independent of hypoxia in locally advanced cervical cancer

A Nilsen, T Hillestad, VE Skingen… - Molecular …, 2022 - Wiley Online Library
Many patients with locally advanced cervical cancer experience recurrence within the
radiation field after chemoradiotherapy. Biomarkers of tumor radioresistance are required to …

miARma-Seq, a comprehensive pipeline for the simultaneous study and integration of miRNA and mRNA expression data

E Andrés-León, AM Rojas - Methods, 2019 - Elsevier
Messenger RNAs (mRNAs) fulfil specific biological roles in cells and, thus, their expression
may be adapted to suit specific circumstances. This is in part achieved through selective …

Computational resources for prediction and analysis of functional miRNA and their targetome

I Monga, M Kumar - Computational Biology of Non-Coding RNA: Methods …, 2019 - Springer
Abstract microRNAs are evolutionarily conserved, endogenously produced, noncoding
RNAs (ncRNAs) of approximately 19–24 nucleotides (nts) in length known to exhibit gene …

Circulating miRNA as a biomarker in oral cancer liquid biopsy

A Roi, S Boia, LC Rusu, CI Roi, ER Boia, M Riviș - Biomedicines, 2023 - mdpi.com
Oral cancer is currently challenging the healthcare system, with a high incidence among the
population and a poor survival rate. One of the main focuses related to this malignancy is the …

[PDF][PDF] Molecular profiling of decompensated cirrhosis by a novel MicroRNA signature

A Garcia Garcia de Paredes… - Hepatology …, 2021 - Wiley Online Library
Noninvasive staging of decompensated cirrhosis is an unmet clinical need. The aims of this
study were to characterize and validate a novel microRNA (miRNA) signature to stage …

The C421A (Q141K) polymorphism enhances the 3′-untranslated region (3′-UTR)-dependent regulation of ATP-binding cassette transporter ABCG2

A Ripperger, RA Benndorf - Biochemical pharmacology, 2016 - Elsevier
The impact of the gout-causing C421A (Q141K) single nucleotide polymorphism (SNP) on
ABC transporter ABCG2 expression and function has been extensively characterized …

NACC1, as a target of MicroRNA-331-3p, regulates cell proliferation in urothelial carcinoma cells

K Morita, T Fujii, H Itami, T Uchiyama, T Nakai… - Cancers, 2018 - mdpi.com
The nucleus accumbens-associated protein 1 (NACC1) is a transcription factor constitutively
expressed in the urothelium, where it regulates cell growth, senescence, autophagy, and …

Computational methods and software tools for functional analysis of miRNA data

A Garcia-Moreno, P Carmona-Saez - Biomolecules, 2020 - mdpi.com
miRNAs are important regulators of gene expression that play a key role in many biological
processes. High-throughput techniques allow researchers to discover and characterize …

[HTML][HTML] A disease-associated microRNA cluster links inflammatory pathways and an altered composition of leukocyte subsets to noninfectious uveitis

FH Verhagen, CPJ Bekker, M Rossato… - … & Visual Science, 2018 - tvst.arvojournals.org
Purpose: The cause of noninfectious uveitis (NIU) is poorly understood but is considered to
be mediated by a complex interplay between genetic, environmental, and—relatively …

Circular RNA circ0001955 promotes cervical cancer tumorigenesis and metastasis via the miR-188-3p/NCAPG2 axis

W Wang, H Luo, J Chang, X Yang, X Zhang… - Journal of Translational …, 2023 - Springer
Abstract Background Circular RNAs (circRNAs) are known to play a crucial role in a variety
of malignancies. However, the precise role of circRNAs in cervical squamous cell carcinoma …