Background MicroRNA (miRNA) has been shown to play a key role in the occurrence and
progression of diseases, making uncovering miRNA-disease associations vital for disease …

Immune-mediated inflammatory diseases (IMIDs) comprise a complex group of pathologies
with diverse etiologies and clinical manifestations. In particular, omics technologies have …

Background The underlying neurobiology of early-life stress (ELS)-induced major
depressive disorder is not clearly understood. Methods In this study, we used maternal …

Computational drug repurposing, also called drug repositioning, is a low cost, promising tool
for finding new uses for existing drugs. With the continued growth of repositories of …

During tumor progression, cancer cells rewire their metabolism to face their bioenergetic
demands. In recent years, microRNAs (miRNAs) have emerged as regulatory elements that …

Background: MicroRNAs (miRNAs) are small non-coding RNAs that control gene expression
at the post-transcriptional level through complementary base pairing with the target mRNA …

FBXW7 is a driver gene in T-cell lymphoblastic neoplasia acting through proteasome
degradation of key proto-oncogenes. FBXW7 encodes three isoforms, α, β and γ, which …

Abstract MicroRNAs (miRNAs), long non-coding RNAs (lncRNAs) and other functional non-
coding RNAs (ncRNAs) have emerged as pivotal regulators involved in multiple biological …

Today, the bioinformatics tool and database development are one of the most significant
research areas in computational biology. Computational biologists are developing diverse …

MicroRNAs have been shown to be able to modulate the tumor microenvironment and the
immune response and hence could be interesting biomarkers and therapeutic targets in …