Breast cancer is the most common type of cancer amongst women worldwide, and
numerous microRNAs (miRNAs/miRs) are involved in the initiation and progression of …

Background Precursor T-cell lymphoblastic lymphomas (T-LBL) are rare aggressive
hematological malignancies that mainly develop in children. As in other cancers, the loss of …

Purpose: This study aimed to investigate in vivo effects of estradiol on the regulation of
hepatic inducible nitric oxide synthase (iNOS) expression in the high fat (HF) diet‐induced …

Many genomic features are defined not by exact sequence matches, but by degenerate
nucleotide motifs that represent multiple compatible matches. While there are databases …

In this chapter we discuss computational methods for the prediction of microRNA (miRNA)
targets. More specifically, we consider machine learning-based approaches and explain …

Reduced biotinidase activity is associated with a spectrum of deficiency ranging from total
deficiency to heterozygous levels, a finding that is not always explained by the pathogenic …

Parkinson's Disease (PD) is a multifaceted neurodegenerative disorder characterised by
complex molecular dysregulations and diverse comorbidities. It is critical to decode the …

MicroRNAs (miRNAs) provide a fundamental layer of regulation in cells. miRNAs act
posttranscriptionally through complementary base-pairing with the 3′-UTR of a target …

Parkinson's disease (PD) is characterized by a range of motor signs, but cognitive
dysfunction is also observed. Supplementation with folic acid and vitamin B12 is expected to …

Cancer is currently recognized as a major cause of mortality worldwide, and, as such, has a
significant impact on public health. Successful early detection strategies are linked to a …