Gene regulation is vital for cellular function and homeostasis, involving diverse mechanisms
controlling specific gene products and contributing to tissue-specific gene expression …

As ubiquitous posttranscriptional regulators of gene expression, microRNAs (miRNAs) play
key roles in cell physiology and function across taxa. In the last two decades, we have …

Adipogenesis is the process of cell differentiation by which mesenchymal stem cells become
adipocytes. Extensive research is ongoing to identify genes, their protein products, and …

The spleen plays an important role in the immune and hematopoietic systems.
Splenomegaly is a frequent consequence of portal hypertension, but the underlying …

RNA sequencing (RNA-Seq) studies have become the gold standard for high-throughput
transcriptome analysis. The amount of data produced by RNA-Seq is unparalleled, providing …

Background NFκB drives acute vascular inflammation by activating gene expression
programs in endothelial cells to promote leukocyte recruitment. Numerous negative …

Recent scientific investigations on P. longifolia leaf extract revealed its anti-cancer property
via the regulation of miR-221-5p. However, there were no further investigations performed to …

Untranslated regions of mRNA (UTRs) are involved in defining the fate of the transcript
through processes such as mRNA localization, degradation, translation initiation regulation …

Invasive revascularisation procedures such as coronary artery bypass grafting (CABG) and
percutaneous coronary intervention (PCI) are used to treat advanced atherosclerosis. The …

Interpretation of omics data is needed to form meaningful hypotheses about disease
mechanisms. Pathway databases give an overview of disease-related processes, while …