Biomarkers in Precision Medicine: The Era of Omics

JJ Vignaux, A André - Digital Medicine, 2019 - Springer
Since the advent of genomics, the suffix “-omics” has been added to the names of many
fields to refer to large-scale studies to identify biomarkers. The-omics data analysis would …

[PDF][PDF] Circulating microRNA and its target genes' role in psoriasis pathogenesis

SA Mostafa, MHS Mohammad, WA Negm, GES Batiha… - academia.edu
-MiR-203 overexpression in psoriasis may be a result of an anti-inflammatory response
because it appears to affect cytokine signaling by targeting both SOCS gene family …

Plasma microRNA profiling for malaria disease: association with severity and P. falciparum biomass

H Gupta, M Rubio, A Sitoe, R Varo, P Cisteró, L Madrid… - medRxiv, 2020 - medrxiv.org
Severe malaria (SM) is a major public health problem in malaria-endemic countries.
Sequestration of Plasmodium falciparum (Pf) infected erythrocytes in vital organs and the …

[PDF][PDF] One layer at a time–disentangling canonical and noncanonical roles of the RNAi pathway in embryonic stem cells

M Schaefer - 2022 - research-collection.ethz.ch
It is well established that gene regulation is a major driver of most cellular processes,
including development and differentiation. MicroRNAs (miRNAs) contribute to gene …

[PDF][PDF] Micrornas circulantes como biomarcadores en cirrosis hepática descompensada

AGG de Paredes, AA MARTÍNEZ, MLG BERMEJO… - 2021 - core.ac.uk
La ascitis refractaria representa una fase de descompensación grave de la cirrosis hepática
caracterizada por la presencia de disfunción circulatoria y elevada mortalidad. Los …

[PDF][PDF] Role of DGCR8 in differentiation and function of murine macrophages

B Killy - 2021 - opus4.kobv.de
One-third of the world population is latently infected with Mycobacterium tuberculosis (Mtb),
the causative agent of tuberculosis (TB). Mtb is an intracellular bacterium that developed …

[HTML][HTML] ARN: Analysis and Visualization System for adipogenic regulation network information

Y Huang, L Wang, L Zan - Scientific Reports, 2016 - nature.com
Adipogenesis is the process of cell differentiation through which preadipocytes become
adipocytes. Lots of research is currently ongoing to identify genes, including their gene …

[HTML][HTML] Disease, Models, Variants and Altered Pathways—Journeying RGD Through the Magnifying Glass

V Petri, GT Hayman, M Tutaj, JR Smith… - Computational and …, 2016 - Elsevier
Understanding the pathogenesis of disease is instrumental in delineating its progression
mechanisms and for envisioning ways to counteract it. In the process, animal models …

[PDF][PDF] Global micro-RNA expression induced by tetramethylpyrazine treatment for spinal cord injuries

Z Yu, Y Zhang, H Zou - Int J Clin Exp Med, 2019 - e-century.us
Spinal cord injuries (SCI) cause serious vascular dysfunction. Tetramethylpyrazine (TMP)
treatment has been shown to promote angiogenesis and improve locomotor and …

[图书][B] Exploring miRNAs as Modulators in Retinal Degeneration: Potential Therapeutic Tools for Inherited Retinal Dystrophies

I Guadagnino - 2021 - search.proquest.com
Inherited retinal dystrophies (IRDs) are a large group of genetic diseases that lead to retinal
degeneration and represent a major cause of vision impairment or blindness. The high …