Glutathione (GSH), the main redox buffer, has long been recognized as a pivotal modulator
of tumor initiation, progression and metastasis. It is also implicated in the resistance of …

Reactive oxygen species (ROS) play an essential role in physiological and pathological
processes. Studies on the regulation of ROS for disease treatments have caused wide …

Nanotherapeutics exhibit unique advantages in clinical outcomes compared with
conventional small molecular drugs. The past three decades have seen intensive research …

In view of certain unique internalization features of the tumor microenvironment
(TME)(mainly including hypoxia, acidity and higher concentrations of H 2 O 2 and GSH) …

Tumor hypoxia and acidity are well-known features in solid tumors that cause
immunosuppression and therapeutic resistance. Herein, we rationally synthesized a …

Cancer radio-immunotherapy, integrating external/internal radiation therapy with immuno-
oncology treatments, emerges in the current management of cancer. A growing number of …

Metastasis of breast carcinoma is commonly realized through lymphatic circulation, which
seriously threatens the lives of breast cancer patients. Therefore, efficient therapy for both …

Improving the effectiveness of cancer therapy will require tools that enable more specific
cancer targeting and improved tumor visualization. Theranostics have the potential for …

Platinum nanoparticles (Pt NPs) have a well-established role as a classic heterogeneous
catalyst. Also, Pt has traditionally been employed as a component of organometallic drug …

Magnetic nanomaterials belong to a class of highly-functionalizable tools for cancer therapy
owing to their intrinsic magnetic properties and multifunctional design that provides a …