[HTML][HTML] MCM3AP-AS1: An indispensable cancer-related LncRNA

X Yu, Q Zheng, Q Zhang, S Zhang, Y He… - Frontiers in Cell and …, 2021 - frontiersin.org
Long non-coding RNAs (lncRNAs) are a class of RNA molecules with transcripts longer than
200 nucleotides that have no protein-coding ability. MCM3AP-AS1, a novel lncRNA, is …

Analysis of Collagen type X alpha 1 (COL10A1) expression and prognostic significance in gastric cancer based on bioinformatics

S Chen, Y Wei, H Liu, Y Gong, Y Zhou, H Yang… - …, 2021 - Taylor & Francis
Collagen type X alpha 1 (COL10A1) is a member of the collagen family and the main matrix
component. However, COL10A1 expression and prognosis relationship remains unclear in …

miRNA-223-3p regulates ECT2 to promote proliferation, invasion, and metastasis of gastric cancer through the Wnt/β-catenin signaling pathway

L Li, P Liu, C He, C Xu - Journal of Cancer Research and Clinical …, 2023 - Springer
Purpose Expression of the guanine nucleotide exchange factor epithelial cell transforming 2
(ECT2) is elevated in gastric cancer (GC) but its biological function in GC is poorly …

[HTML][HTML] The biological functions and related signaling pathways of SPON2

J Zhang, G Liu, Y Liu, P Yang, J Xie, X Wei - Frontiers in Oncology, 2024 - frontiersin.org
Spondin-2 (SPON2), also referred to as M-spondin or DIL-1, is a member of the extracellular
matrix protein family known as Mindin-F-spondin (FS). SPON2 can be used as a broad …

[HTML][HTML] Tumor-derived exosomal HOTAIRM1 regulates SPON2 in CAFs to promote progression of lung adenocarcinoma

Z Chen, C Bian, J Huang, X Li, L Chen, X Xie, Y Xia… - Discover Oncology, 2022 - Springer
Objective SPON2 is one of the extracellular matrix proteins, which is closely related to the
progression of a variety of tumors including non-small cell lung cancer (NSCLC), but its …

[HTML][HTML] Mindin (SPON2) is essential for cutaneous fibrogenesis in a mouse model of systemic sclerosis

I Rana, S Kataria, TL Tan, EY Hajam… - Journal of Investigative …, 2023 - Elsevier
Systemic sclerosis is a fibrotic disease that initiates in the skin and progresses to internal
organs, leading to a poor prognosis. Unraveling the etiology of a chronic, multifactorial …

[HTML][HTML] Epigenetic regulation of MAP3K8 in EBV-associated gastric carcinoma

G Roy, T Yang, S Liu, YL Luo, Y Liu… - International Journal of …, 2023 - mdpi.com
Super-enhancers (SEs) regulate gene expressions, which are critical for cell type-identity
and tumorigenesis. Although genome wide H3K27ac profiling have revealed the presence …

SPON2 promotes the bone metastasis of lung adenocarcinoma via activation of the NF-κB signaling pathway

M Wu, D Kong, Y Zhang - Bone, 2023 - Elsevier
Bone metastasis severely affects the life span and quality of life of survivors of lung
adenocarcinoma (ADC). There is a pressing need to identify viable biomarkers for this …

[HTML][HTML] SLC6A8 is involved in the progression of non-small cell lung cancer through the Notch signaling pathway

Y Feng, X Guo, H Tang - Annals of Translational Medicine, 2021 - ncbi.nlm.nih.gov
Background Solute carrier family 6 member 8 (SLC6A8) is known to be involved in the
development of human tumors; however, the effect of SLC6A8 on the growth of non-small …

[HTML][HTML] Comprehensive analysis of the oncogenic and immunological role of SPON2 in human tumors

J Tang, Q Huang, X Li, S Gu - Medicine, 2023 - journals.lww.com
Background: Sapiens spondin-2 (SPON2) is a protein found in the extracellular matrix that
plays a role in a number of processes, including immune reactions and cell adhesion, and is …