We reviewed the relevant syphilis diagnostic literature to address the following question:
what are the performance characteristics, stratified by the stage of syphilis, for …

Neurosyphilis is caused by the bacterium Treponema pallidum subspecies pallidum (T.
pallidum). The organism gains entry into the central nervous system (CNS) early (primary …

This report provides new CDC recommendations for tests that can support a diagnosis of
syphilis, including serologic testing and methods for the identification of the causative agent …

Multiple studies around the world suggest that syphilis is re-emerging. Ocular syphilis–with a
wide range of presentations, most of which are subtypes of uveitis–has become an …

Recent reports from different world regions suggest ocular syphilis is re-emerging, in parallel
with an increasing incidence of the systemic infection globally. We conducted a large …

Background Syphilitic uveitis is re-emerging alongside the systemic infection. In July 2017,
an international group of uveitis-specialised ophthalmologists formed the International …

Doxycycline is a second-generation tetracycline, available worldwide for half a century. It is
an inexpensive broad-spectrum antimicrobial agent largely used in the management of …

Background Ocular involvement can occur at any stage of syphilis. Prompt diagnosis and
proper treatment of ocular syphilis are vital to avoid long‐term consequences. Objectives To …

We describe the frequency, demographic and clinical features, and visual outcomes of
ocular syphilis infections observed during 2012–2015 at a tertiary reference center in Paris …

Objective To explore the associations between the use of immune checkpoint inhibitors
(ICIs) and the risk of developing uveitis among cancer patients. Methods Cancer patients …