[HTML][HTML] A comprehensive review on the benefits and problems of curcumin with respect to human health

S Liu, J Liu, L He, L Liu, B Cheng, F Zhou, D Cao, Y He - Molecules, 2022 - mdpi.com
Curcumin is the most important active component in turmeric extracts. Curcumin, a natural
monomer from plants has received a considerable attention as a dietary supplement …

TFOS Lifestyle: impact of nutrition on the ocular surface

M Markoulli, S Ahmad, J Arcot, R Arita… - The ocular …, 2023 - Elsevier
Nutrients, required by human bodies to perform life-sustaining functions, are obtained from
the diet. They are broadly classified into macronutrients (carbohydrates, lipids, and proteins) …

[HTML][HTML] Obstacles against the Marketing of Curcumin as a Drug

K Hassanzadeh, L Buccarello, J Dragotto… - International journal of …, 2020 - mdpi.com
Among the extensive public and scientific interest in the use of phytochemicals to prevent or
treat human diseases in recent years, natural compounds have been highly investigated to …

Uncoupling proteins in the mitochondrial defense against oxidative stress

DT Hass, CJ Barnstable - Progress in retinal and eye research, 2021 - Elsevier
Oxidative stress is a major component of most major retinal diseases. Many extrinsic anti-
oxidative strategies have been insufficient at counteracting one of the predominant intrinsic …

[HTML][HTML] Recent developments of nanostructures for the ocular delivery of natural compounds

MS Razavi, P Ebrahimnejad, Y Fatahi… - Frontiers in …, 2022 - frontiersin.org
Ocular disorders comprising various diseases of the anterior and posterior segments are
considered as the main reasons for blindness. Natural products have been identified as …

[HTML][HTML] Detection of diabetic retinopathy using extracted 3D features from OCT images

M Elgafi, A Sharafeldeen, A Elnakib, A Elgarayhi… - Sensors, 2022 - mdpi.com
Diabetic retinopathy (DR) is a major health problem that can lead to vision loss if not treated
early. In this study, a three-step system for DR detection utilizing optical coherence …

Nanosuspension-loaded dissolving bilayer microneedles for hydrophobic drug delivery to the posterior segment of the eye

Y Wu, LK Vora, D Mishra, MF Adrianto, S Gade… - Biomaterials …, 2022 - Elsevier
Intravitreal injections (IVT) are regarded as the gold standard for effective delivery of
hydrophobic drugs to the back of the eye. However, as a highly invasive procedure, the …

[HTML][HTML] The protective effects of flavonoids in cataract formation through the activation of Nrf2 and the inhibition of MMP-9

A Hilliard, P Mendonca, TD Russell, KFA Soliman - Nutrients, 2020 - mdpi.com
Cataracts account for over half of global blindness. Cataracts formations occur mainly due to
aging and to the direct insults of oxidative stress and inflammation to the eye lens. The …

[HTML][HTML] Curcumin is a Potential Adjuvant to Alleviates Diabetic Retinal Injury via Reducing Oxidative Stress and Maintaining Nrf2 Pathway Homeostasis

T Xie, X Chen, W Chen, S Huang, X Peng… - Frontiers in …, 2021 - frontiersin.org
Curcumin is a natural polyphenol compound with anti-diabetic, anti-oxidative, and anti-
inflammatory effects. Although many studies have reported the protective effect of curcumin …

Adjuvant therapies in diabetic retinopathy as an early approach to delay its progression: the importance of oxidative stress and inflammation

RR Robles-Rivera… - Oxidative medicine …, 2020 - Wiley Online Library
Diabetes mellitus (DM) is a progressive disease induced by a sustained state of chronic
hyperglycemia that can lead to several complications targeting highly metabolic cells …