Human metabolic diseases can be mimicked in rodents by using dietary interventions such
as high fat diets (HFD). Nonalcoholic fatty liver disease (NAFLD) develops as a result of HFD …

Recent studies showed that germ‐free (GF) mice are resistant to obesity when consuming a
high‐fat, high‐carbohydrate Western diet. However, it remains unclear what mechanisms …

The manner in which insulin resistance impinges on hepatic mitochondrial function is
complex. Although liver insulin resistance is associated with respiratory dysfunction, the …

Nonalcoholic fatty liver disease is associated with hepatic insulin resistance and may result
primarily from increased hepatic de novo lipogenesis (PRIM) or secondarily from adipose …

Aging is often accompanied by a decline in mitochondrial mass and function in different
tissues. Additionally, cell resistance to stress is frequently found to be prevented by higher …

Non-alcoholic fatty liver disease is a primary hepatic manifestation of obesity and an
important adverse metabolic syndrome trait. Animal models of diet-induced obesity promote …

Gallic acid (GA) is a simple polyphenol found in food and traditional Chinese medicine.
Here, we determined the effects of GA administration in a combined mouse model of high-fat …

Hepatic ketogenesis provides a vital systemic fuel during fasting because ketone bodies are
oxidized by most peripheral tissues and, unlike glucose, can be synthesized from fatty acids …

OBJECTIVE: Hypothalamic centers integrate external signals of nutrient availability and
energy status and initiate responses to maintain homeostasis. Quantifying changes in …

This work investigates the effect of a soy-based probiotic drink (Enterococcus faecium CRL
183 and Bifidobacterium longum ATCC 15707) on the fecal microbiota composition, body …