Hedgehog signaling in tissue homeostasis, cancers, and targeted therapies

J Jing, Z Wu, J Wang, G Luo, H Lin, Y Fan… - Signal Transduction and …, 2023 - nature.com
The past decade has seen significant advances in our understanding of Hedgehog (HH)
signaling pathway in various biological events. HH signaling pathway exerts its biological …

The role of Shh signalling pathway in central nervous system development and related diseases

X Li, Y Li, S Li, H Li, C Yang, J Lin - Cell biochemistry and …, 2021 - Wiley Online Library
Sonic hedgehog (Shh) plays important roles in developmental of vertebrate animal central
nervous system (CNS), and Gli is its downstream signal molecule. Shh signalling is …

Determination of a tumor-promoting microenvironment in recurrent medulloblastoma: a multi-omics study of cerebrospinal fluid

B Reichl, L Niederstaetter, T Boegl, B Neuditschko… - Cancers, 2020 - mdpi.com
Molecular classification of medulloblastoma (MB) is well-established and reflects the cell
origin and biological properties of tumor cells. However, limited data is available regarding …

TOP2A correlates with poor prognosis and affects radioresistance of medulloblastoma

Y Zhang, H Yang, L Wang, H Zhou, G Zhang… - Frontiers in …, 2022 - frontiersin.org
Radiotherapy remains the standard treatment for medulloblastoma (MB), and the
radioresistance contributes to tumor recurrence and poor clinical outcomes. Nuclear DNA …

Cytotoxicity of poly-guanidine in medulloblastoma cell lines

G Gallo-Oller, TD de Ståhl, A Alaiya, S Nilsson… - Investigational New …, 2023 - Springer
Medulloblastoma (MB) is the most common pediatric brain tumor. The therapy frequently
causes serious side effects, and new selective therapies are needed. MB expresses hyper …

Methylation profiling of medulloblastoma in a clinical setting permits sub-classification and reveals new outcome predictions

M Alharbi, N Mobark, Y Bashawri, L Abu Safieh… - Frontiers in …, 2020 - frontiersin.org
Medulloblastoma (MB) is the most common childhood malignant brain tumor and is a
leading cause of cancer-related death in children. DNA methylation profiling has rapidly …

[HTML][HTML] 101 例儿童复发髓母细胞瘤的序贯治疗生存分析

孙艳玲, 刘晶晶, 杜淑旭, 武万水… - Chinese Journal of …, 2021 - ncbi.nlm.nih.gov
101例儿童复发髓母细胞瘤的序贯治疗生存分析- PMC Back to Top Skip to main content NIH
NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation …

SHH 型髓母细胞瘤患儿临床特点及预后因素分析

高文超, 孙艳玲, 李苗, 任思其, 杜淑旭… - 临床儿科 …, 2022 - jcp.xinhuamed.com.cn
目的回顾性分析SHH (sonic hedgehog) 型髓母细胞瘤(medulloblastoma, MB) 患儿的临床特点,
探讨其预后影响因素. 方法回顾性分析2015 年6 月至2019 年10 月儿科收治的SHH 型MB …

Survival of children with recurrent medulloblastoma undergoing sequential therapy: an analysis of 101 cases.

SUN Yan-Ling, LIU Jing-Jing… - Chinese Journal of …, 2021 - search.ebscohost.com
Objective To study the clinical features of children with recurrent medulloblastoma (MB) and
treatment regimens. Methods A retrospective analysis was performed on 101 children with …

Real-life experience with a “modified-MEMMAT” regimen for relapsed medulloblastoma

A Cacchione, G Del Baldo, F D'Antonio, V Di Ruscio… - 2024 - researchsquare.com
Real-life experience with a “modified-MEMMAT” regimen for relapsed medulloblastoma Page 1
Page 1/22 Real-life experience with a “modi ed-MEMMAT” regimen for relapsed …